Imaging matrix metalloproteinase activity in multiple sclerosis as a specific marker of leukocyte penetration of the blood-brain barrier

…, J Song, K Kopka, A Faust, C Wenning… - Science translational …, 2016 - science.org
The enzymes gelatinase A/matrix metalloproteinase-2 (MMP-2) and gelatinase B/MMP-9
are essential for induction of neuroinflammatory symptoms in experimental autoimmune …

Contributory role of fluorine 18-fluorodeoxyglucose positron emission tomography/computed tomography in the diagnosis and clinical management of infections in …

…, S Mastrobuoni, S Alles, C Wenning… - The Annals of thoracic …, 2016 - Elsevier
Background The current study sought to demonstrate the advantages offered by fluorine 18-fluorodeoxyglucose
( 18 F-FDG) positron emission tomography/computed tomography (PET/…

[18F]FDG PET/CT outperforms [18F]FDG PET/MRI in differentiated thyroid cancer

A Vrachimis, MC Burg, C Wenning, T Allkemper… - European journal of …, 2016 - Springer
Purpose To evaluate the diagnostic potential of PET/MRI with [ 18 F]FDG in comparison to
PET/CT in patients with differentiated thyroid cancer suspected or known to have …

Fluorine-18 fluorodeoxyglucose positron emission tomography/computed tomography for improving diagnosis of infection in patients on CF-LVAD: longing for more ' …

…, M Scherer, JR Sindermann, C Wenning - European Heart …, 2018 - academic.oup.com
Aim Presence and consequent extent of infection in patients on continuous-flow left ventricular
assist devices (CF-LVADs) can be challenging with the current diagnostic tools. The …

Preoperative 11C-Methionine PET/CT Enables Focussed Parathyroidectomy in MIBI-SPECT Negative Parathyroid Adenoma

C Lenschow, P Gassmann, C Wenning… - World journal of …, 2015 - Springer
Background Precise preoperative localization is essential for focussed parathyroidectomy.
The imaging standard consists of cervical ultrasonography (cUS) and 99m Tc-MIBI-SPECT (…

Serial F-18-FDG PET/CT distinguishes inflamed from stable plaque phenotypes in shear-stress induced murine atherosclerosis

C Wenning, C Kloth, MT Kuhlmann, AH Jacobs… - Atherosclerosis, 2014 - Elsevier
Background Detection of inflamed atherosclerotic plaques is of crucial importance. The
carotid artery cuff-model in ApoE −/− mice results in shear-stress induced atherosclerosis with …

Metabolic volume performs better than SUVmax in the detection of left ventricular assist device driveline infection

…, A Vrachimis, JR Sindermann, C Wenning - European Journal of …, 2017 - Springer
Purpose A continuous-flow left ventricular assist device (LVAD) is a new and highly
promising therapy in supporting end-stage heart failure patients, either bridging them to heart …

Non-FDG imaging of atherosclerosis: will imaging of MMPs assess plaque vulnerability?

…, B Waschkau, M Kuhlmann, C Wenning… - Journal of nuclear …, 2012 - Elsevier
Acute ruptures of atherosclerotic plaques with subsequent occlusion account for the vast
majority of clinical events such as myocardial infarction or stroke. New imaging approaches …

[HTML][HTML] Pulmonary vein isolation in patients with paroxysmal atrial fibrillation is associated with regional cardiac sympathetic denervation

C Wenning, PS Lange, C Schülke, A Vrachimis… - EJNMMI research, 2013 - Springer
Background Circumferential pulmonary vein isolation (PVI) is the cornerstone of the current
state-of-the-art management of atrial fibrillation (AF). However, the precise mechanisms …

[68Ga]DOTATATE PET/MRI and [18F]FDG PET/CT are complementary and superior to diffusion-weighted MR imaging for radioactive-iodine-refractory differentiated …

A Vrachimis, L Stegger, C Wenning, B Noto… - European journal of …, 2016 - Springer
Purpose The purpose of this study was to determine whether [ 68 Ga]DOTATATE PET/MRI
with diffusion-weighted imaging (DWI) can replace or complement [ 18 F]FDG PET/CT in …