Integrative genome analyses identify key somatic driver mutations of small-cell lung cancer
…, T Zander, R Menon, M Koker, I Dahmen, C Müller… - Nature …, 2012 - nature.com
Small-cell lung cancer (SCLC) is an aggressive lung tumor subtype with poor prognosis 1 ,
2 , 3 . We sequenced 29 SCLC exomes, 2 genomes and 15 transcriptomes and found an …
2 , 3 . We sequenced 29 SCLC exomes, 2 genomes and 15 transcriptomes and found an …
Comprehensive genomic profiles of small cell lung cancer
…, X Lu, L Fernández-Cuesta, G Bosco, C Müller… - Nature, 2015 - nature.com
We have sequenced the genomes of 110 small cell lung cancers (SCLC), one of the deadliest
human cancers. In nearly all the tumours analysed we found bi-allelic inactivation of TP53 …
human cancers. In nearly all the tumours analysed we found bi-allelic inactivation of TP53 …
ESC Guidelines on the diagnosis and treatment of peripheral artery diseases: document covering atherosclerotic disease of extracranial carotid and vertebral …
…, A Micari, M Mosseri, C Müller… - European heart …, 2011 - academic.oup.com
Cardiovascular diseases (CVDs) are the leading cause of death and disability in Europe,
posing a great social and economic burden. Coronary artery disease (CAD) is the cause of …
posing a great social and economic burden. Coronary artery disease (CAD) is the cause of …
Procalcitonin guidance of antibiotic therapy in community-acquired pneumonia: a randomized trial
…, D Stolz, R Bingisser, C Muller… - American journal of …, 2006 - atsjournals.org
Rationale: In patients with community-acquired pneumonia, guidelines recommend antibiotic
treatment for 7 to 21 d. Procalcitonin is elevated in bacterial infections, and its dynamics …
treatment for 7 to 21 d. Procalcitonin is elevated in bacterial infections, and its dynamics …
[HTML][HTML] Sparse and compositionally robust inference of microbial ecological networks
16S ribosomal RNA (rRNA) gene and other environmental sequencing techniques provide
snapshots of microbial communities, revealing phylogeny and the abundances of microbial …
snapshots of microbial communities, revealing phylogeny and the abundances of microbial …
Switching on and off fear by distinct neuronal circuits
Switching between exploratory and defensive behaviour is fundamental to survival of many
animals, but how this transition is achieved by specific neuronal circuits is not known. Here, …
animals, but how this transition is achieved by specific neuronal circuits is not known. Here, …
Encoding of conditioned fear in central amygdala inhibitory circuits
The central amygdala (CEA), a nucleus predominantly composed of GABAergic inhibitory
neurons, is essential for fear conditioning. How the acquisition and expression of conditioned …
neurons, is essential for fear conditioning. How the acquisition and expression of conditioned …
Stanley Fahn Lecture 2005: The staging procedure for the inclusion body pathology associated with sporadic Parkinson's disease reconsidered
H Braak, JR Bohl, CM Müller, U Rüb… - … : official journal of the …, 2006 - Wiley Online Library
The synucleinopathy known as sporadic Parkinson's disease (PD) is a multisystem disorder
that severely damages predisposed nerve cell types in circumscribed regions of the human …
that severely damages predisposed nerve cell types in circumscribed regions of the human …
Antibiotic treatment of exacerbations of COPD: a randomized, controlled trial comparing procalcitonin-guidance with standard therapy
…, J Leuppi, D Miedinger, C Müller, P Huber, B Müller… - Chest, 2007 - Elsevier
Background:Therapy with antibiotics influences recovery only in selected cases of COPD
exacerbations. We evaluated the efficacy and safety of procalcitonin guidance compared to …
exacerbations. We evaluated the efficacy and safety of procalcitonin guidance compared to …
Doping approaches for organic semiconductors
Electronic doping in organic materials has remained an elusive concept for several decades.
It drew considerable attention in the early days in the quest for organic materials with high …
It drew considerable attention in the early days in the quest for organic materials with high …