Iodo-resiniferatoxin, a new potent vanilloid receptor antagonist

P Wahl, C Foged, S Tullin, C Thomsen - Molecular pharmacology, 2001 - ASPET
The highly potent vanilloid receptor (VR) agonist resiniferatoxin has been radiolabeled with
125 I, and the pharmacology to the cloned rodent VR, VR1, and the endogenous VR in rat …

Measurement of Striatal and Extrastriatal Dopamine D1 Receptor Binding Potential With [11C]NNC 112 in Humans: Validation and Reproducibility

…, JJ Mann, R Van Heertum, C Foged… - Journal of Cerebral …, 2000 - journals.sagepub.com
To evaluate the postulated role of extrastriatal D 1 receptors in human cognition and
psychopathology requires an accurate and reliable method for quantification of these receptors in …

PET examination of [11C]NNC 687 and [11C]NNC 756 as new radioligands for the D1-dopamine receptor

…, C Halldin, CG Swahn, G Sedvall, C Foged… - …, 1993 - Springer
The benzazepines NNC 687 and NNC 756 have in animal studies been described as selective
D 1 -dopamine receptor antagonists. Both compounds have been labeled with 11 C for …

[PDF][PDF] Carbon-11-NNC 112: a radioligand for PET examination of striatal and neocortical D1-dopamine receptors

C Halldin, C Foged, YH Chou, P Karlsson… - Journal of Nuclear …, 1998 - Soc Nuclear Med
Methods: The active (+)-and inactive (-)-enantiomers of [11C] NNC 112 were radiolabeled
using the N-methylation approach and were examined by PET in cynomolgus monkeys and …

[HTML][HTML] The hypothalamic satiety peptide CART is expressed in anorectic and non-anorectic pancreatic islet tumors and in the normal islet of Langerhans

…, ME Judge, S Hastrup, L Thim, BS Wulff, C Foged… - FEBS letters, 1999 - Elsevier
The hypothalamic satiety peptide CART (cocaine and amphetamine regulated transcript) is
expressed at high levels in anorectic rat glucagonomas but not in hypoglycemic insulinomas. …

PET studies of binding competition between endogenous dopamine and the D1 radiotracer [11C]NNC 756

…, I Lombardo, R Van Heertum, JJ Mann, C Foged… - Synapse, 1999 - Wiley Online Library
NNC 756 ((+)‐8‐chloro‐5‐(2,3‐dihydrobenzofuran‐7‐yl)‐7‐hydroxy‐3‐methyl‐2,3,4,5‐tetrahydro‐1H‐3‐benzazepine)
is a new high affinity dopamine (DA) D 1 receptor antagonist. …

PET Study of the M1-Agonists [11C]Xanomeline and [11C]Butylthio-TZTP in Monkey and Man

…, F Bymaster, H Shannon, C Foged… - Dementia and Geriatric …, 1996 - karger.com
Xanomeline, a substituted TZTP, is a new M 1 selective muscarinic agonist in clinical trials
for Alzheimer''s disease. The brain uptake of [ 11 C]xanomeline and the analog [ 11 C]butylthio…

[3H]‐thioperamide as a radioligand for the histamine H3 receptor in rat cerebral cortex

…, R Leurs, TS Wu, GD Prell, C Foged… - British journal of …, 1996 - Wiley Online Library
1 The purpose of the present study was to characterize the binding of the histamine H 3
receptor antagonist, [ 3 H]‐thioperamide, to rat cerebral cortical membranes. 2 The binding of [ 3 …

[11C] NNC 687 and [11C] NNC 756, dopamine D-1 receptor ligands. Preparation, autoradiography and PET investigation in monkey

C Halldin, C Foged, L Farde, P Karlsson… - Nuclear medicine and …, 1993 - Elsevier
NNC 687 and NNC 756 [(+)-5-(2,3-dihydrobenzofuran-7-yl)-7-hydroxy-3-methyl-8-nitro-2,3,4,5-tetrahydro-1H-3-benzazepine
and (+)-8-chloro-5-(2,3-dihydrobenzofuran-7-yl)-7-hydroxy-…

Benzodiazepine receptor equilibrium constants for flumazenil and midazolam determined in humans with the single photon emission computer tomography tracer …

…, L Friberg, S Holm, S Wammen, C Foged… - European journal of …, 1993 - Elsevier
This study is based on the steady state method for the calculation of K d values recently
described by Lassen (J. Cereb. Blood Flow Metab. 12 (1992), 709), in which a constant infusion …