Lung cancer—a fractal viewpoint

…, TA Hensing, HJ Zhang, CT Chen… - Nature reviews Clinical …, 2015 - nature.com
Fractals are mathematical constructs that show self-similarity over a range of scales and non-integer
(fractal) dimensions. Owing to these properties, fractal geometry can be used to …

Accurate three-dimensional registration of CT, PET, and/or MR images of the brain

CA Pelizzari, GTY Chen, DR Spelbring… - Journal of computer …, 1989 - journals.lww.com
A surface matching technique has been developed to register multiple imaging scans of the
brain in three dimensions, with accuracy on the order of the image pixel sizes. Anatomic …

Rational design of silicon structures for optically controlled multiscale biointerfaces

…, RCS Wong, CM Kao, CT Chen… - Nature biomedical …, 2018 - nature.com
Silicon-based materials have been widely used in biological applications. However, remotely
controlled and interconnect-free silicon configurations have been rarely explored, because …

Near‐infrared mesoporous silica nanoparticles for optical imaging: characterization and in vivo biodistribution

…, YC Chen, NT Chen, J Souris, CT Chen… - Advanced Functional …, 2009 - Wiley Online Library
The characterization of near‐infrared (NIR) mesoporous silica nanoparticles (MSN) suitable
for in vivo optical imaging with high efficiency is presented. Trimethylammonium groups …

Surface charge-mediated rapid hepatobiliary excretion of mesoporous silica nanoparticles

JS Souris, CH Lee, SH Cheng, CT Chen, CS Yang… - Biomaterials, 2010 - Elsevier
Nanoparticle-assisted drug delivery has been emerging as an active research area in
recent years. The in vivo biodistribution of nanoparticle and its following mechanisms of …

Prognostic value of metabolic tumor burden on 18F-FDG PET in nonsurgical patients with non-small cell lung cancer

…, R Kampalath, MC Shih, N Shimada, S Chen… - European journal of …, 2012 - Springer
Purpose The objective of this study was to assess the prognostic value of metabolic tumor
burden on 2-deoxy-2-[ 18 F]fluoro-D-glucose ( 18 F-FDG) positron emission tomography (PET)/…

The novel role of the mu opioid receptor in lung cancer progression: a laboratory investigation

…, LM Gerhold, PJ LaRiviere, CT Chen… - Anesthesia & …, 2011 - journals.lww.com
BACKGROUND: The possibility that μ opioid agonists can influence cancer recurrence is a
subject of recent interest. Epidemiologic studies suggested that there were differences in …

Tri-functionalization of mesoporous silica nanoparticles for comprehensive cancer theranostics—the trio of imaging, targeting and therapy

SH Cheng, CH Lee, MC Chen, JS Souris… - Journal of Materials …, 2010 - pubs.rsc.org
In this work we report the development of the tri-functionalized mesoporous silica nanoparticles
(MSNs) for use as theranostic compounds that orchestrate the trio of imaging, target and …

PGC1α-mediated mitofusin-2 deficiency in female rats and humans with pulmonary arterial hypertension

…, HJ Zhang, M Han, CR Haney, CT Chen… - American journal of …, 2013 - atsjournals.org
Rationale: Pulmonary arterial hypertension (PAH) is a lethal, female-predominant, vascular
disease. Pathologic changes in PA smooth muscle cells (PASMC) include excessive …

Automatic segmentation of liver structure in CT images

KT Bae, ML Giger, CT Chen, CE Kahn Jr - Medical physics, 1993 - Wiley Online Library
The segmentation and three‐dimensional representation of the liver from a computed
tomography (CT) scan is an important step in many medical applications, such as in the surgical …