In vivo SPECT Imaging of Amyloid-β deposition with radioiodinated imidazo [1, 2-a] pyridine derivative DRM106 in a mouse model of Alzheimer's disease
…, K Shima, O Fujimoto, C Kitamura… - Journal of Nuclear …, 2015 - Soc Nuclear Med
Noninvasive determination of amyloid-β peptide (Aβ) deposition has important significance
for early diagnosis and medical intervention for Alzheimer's disease (AD). In the present study…
for early diagnosis and medical intervention for Alzheimer's disease (AD). In the present study…
[HTML][HTML] Calibrated scintigraphic imaging procedures improve quantitative assessment of the cardiac sympathetic nerve activity
K Okuda, K Nakajima, C Kitamura, Y Kirihara… - Scientific Reports, 2020 - nature.com
The 123 I-labeled meta-iodobenzylguanidine (MIBG) is an analogue of noradrenaline that
can evaluate cardiac sympathetic activity in scintigraphy. Quantitative analysis of 123 I-MIBG …
can evaluate cardiac sympathetic activity in scintigraphy. Quantitative analysis of 123 I-MIBG …
Synthesis and biological evaluation of novel radioiodinated imidazopyridine derivatives for amyloid-β imaging in Alzheimer's disease
…, K Taguchi, H Shiraishi, O Fujimoto, C Kitamura… - Bioorganic & Medicinal …, 2014 - Elsevier
Non-invasive detection for amyloid-β peptide (Aβ) deposition has important significance for
the early diagnosis and medical intervention for Alzheimer’s disease (AD). In this study, we …
the early diagnosis and medical intervention for Alzheimer’s disease (AD). In this study, we …
Biological evaluation of the radioiodinated imidazo [1, 2-a] pyridine derivative DRK092 for amyloid-β imaging in mouse model of Alzheimer's disease
…, H Shiraishi, K Shima, O Fujimoto, C Kitamura… - Neuroscience …, 2014 - Elsevier
Non-invasive determination of amyloid-β peptide (Aβ) deposition has important significance
for early diagnosis and medical intervention in Alzheimer's disease (AD). In this study, we …
for early diagnosis and medical intervention in Alzheimer's disease (AD). In this study, we …
Machine learning-based prediction of conversion coefficients for I-123 metaiodobenzylguanidine heart-to-mediastinum ratio
K Okuda, K Nakajima, C Kitamura, M Ljungberg… - Journal of Nuclear …, 2023 - Elsevier
Purpose We developed a method of standardizing the heart-to-mediastinal ratio in 123 I-labeled
meta-iodobenzylguanidine (MIBG) images using a conversion coefficient derived from a …
meta-iodobenzylguanidine (MIBG) images using a conversion coefficient derived from a …
Comparison of Taiwanese and European Calibration Factors for Heart-to-Mediastinum Ratio in Multicenter 123I-mIBG Phantom Studies
…, DO Verschure, HJ Verberne, C Kitamura - Annals of Nuclear …, 2023 - jstage.jst.go.jp
Background: Cross-calibration of 123 I-labeled meta-iodobenzylguanidine (mIBG)
myocardial-derived indices is essential to extrapolate findings from several clinical centers. Here, we …
myocardial-derived indices is essential to extrapolate findings from several clinical centers. Here, we …
Standardization of 123I-meta-iodobenzylguanidine Heart-To-Mediastinum Ratio: Technical Aspects
K Okuda, K Nakajima, C Kitamura… - … Applications and Future …, 2018 - books.google.com
The heart-to-mediastinum ratio (HMR) in planar images has been used for the evaluation of
cardiac 123I-meta-iodobenzylguanidine (MIBG) uptake. However, the HMR values are …
cardiac 123I-meta-iodobenzylguanidine (MIBG) uptake. However, the HMR values are …
Multicenter phantom study of characteristics of gamma cameras with LEHR collimators in cardiac 123I-MIBG imaging
K Okuda, K Nakajima, C Kitamura, M Hori, Y Kirihara… - 2016 - Soc Nuclear Med
1916 Objectives We have proposed a standardization method for the determination of 123 I-metaiodobenzylguanidine
(MIBG) heart-to-mediastinum ratio for the calibration of the …
(MIBG) heart-to-mediastinum ratio for the calibration of the …
In Vivo SPECT Imaging of Amyloid-β Deposition with Radioiodinated Imidazo [1, 2-α] pyridine Derivative DRM106 in Mouse Model of Alzheimer's Disease
…, K Shima, O Fujimoto, C Kitamura… - Journal of Nuclear …, 2014 - Soc Nuclear Med
Non-invasive determination of amyloid-β peptide (Aβ) deposition has important significance
for early diagnosis and medical intervention for Alzheimer’s disease (AD). In the present …
for early diagnosis and medical intervention for Alzheimer’s disease (AD). In the present …
[PDF][PDF] P1-277 SPECT IMAGING FOR AMYLOID PLAQUES WITH A NOVEL RADIOIODINATED LIGAND IN AN ALZHEIMER'S DISEASE MODEL
…, K Shima, K Uchida, O Fujimoto, C Kitamura… - Alzheimer's & …, 2014 - academia.edu
Background: Non-invasive determination for amyloid-b peptide (A b) deposition has
important significance for early diagnosis and medical intervention to Alzheimer’s disease (AD). …
important significance for early diagnosis and medical intervention to Alzheimer’s disease (AD). …