Evaluation of toxicity and efficacy of 186Re-hydroxyethylidene diphosphonate in patients with painful bone metastases of prostate or breast cancer
…, P Depreux, P Vennin, A Caty, C Sulman - Journal of Nuclear …, 2000 - Soc Nuclear Med
Twenty-eight patients (12 men with prostate cancer, 16 women with breast cancer) were
included in a phase II trial to evaluate the efficacy of 186 Re-hydroxyethylidene diphosphonate (…
included in a phase II trial to evaluate the efficacy of 186 Re-hydroxyethylidene diphosphonate (…
[PDF][PDF] Study on urban healthcare consumption in northern France.
J Salleron, A Duhamel, C Sulman, V Deken… - Studies in health …, 2008 - academia.edu
In Lille (a large city in northern France), the municipal council has set up an Health Observatory
in order to provide health information on the city's population, promote educational …
in order to provide health information on the city's population, promote educational …
[PDF][PDF] MST4 phosphorylation of ATG4B regulates autophagic activity, tumorigenicity, and radioresistance in glioblastoma
…, JA Kessler, R Nishikawa, I Nakano, EP Sulman… - Cancer cell, 2017 - cell.com
ATG4B stimulates autophagy by promoting autophagosome formation through reversible
modification of ATG8. We identify ATG4B as a substrate of mammalian sterile20-like kinase (…
modification of ATG8. We identify ATG4B as a substrate of mammalian sterile20-like kinase (…
[PDF][PDF] PRMT6 methylation of RCC1 regulates mitosis, tumorigenicity, and radiation response of glioblastoma stem cells
…, JA Kessler, R Stupp, I Nakano, EP Sulman… - Molecular cell, 2021 - cell.com
Aberrant cell proliferation is a hallmark of cancer, including glioblastoma (GBM). Here we
report that protein arginine methyltransferase (PRMT) 6 activity is required for the proliferation, …
report that protein arginine methyltransferase (PRMT) 6 activity is required for the proliferation, …
[PDF][PDF] Identification of a CpG island methylator phenotype that defines a distinct subgroup of glioma
We have profiled promoter DNA methylation alterations in 272 glioblastoma tumors in the
context of The Cancer Genome Atlas (TCGA). We found that a distinct subset of samples …
context of The Cancer Genome Atlas (TCGA). We found that a distinct subset of samples …
[PDF][PDF] Tumor evolution of glioma-intrinsic gene expression subtypes associates with immunological changes in the microenvironment
We leveraged IDH wild-type glioblastomas, derivative neurospheres, and single-cell gene
expression profiles to define three tumor-intrinsic transcriptional subtypes designated as …
expression profiles to define three tumor-intrinsic transcriptional subtypes designated as …
[HTML][HTML] Epigenetic activation of WNT5A drives glioblastoma stem cell differentiation and invasive growth
…, JJ Phillips, MS Berger, DJ Spring, J Hu, EP Sulman… - Cell, 2016 - cell.com
Glioblastoma stem cells (GSCs) are implicated in tumor neovascularization, invasiveness,
and therapeutic resistance. To illuminate mechanisms governing these hallmark features, we …
and therapeutic resistance. To illuminate mechanisms governing these hallmark features, we …
Chromosome 19 annotations with disease speciation: a first report from the Global Research Consortium
A first research development progress report of the Chromosome 19 Consortium with members
from Sweden, Norway, Spain, United States, China and India, a part of the Chromosome-…
from Sweden, Norway, Spain, United States, China and India, a part of the Chromosome-…
[HTML][HTML] Most human non-GCIMP glioblastoma subtypes evolve from a common proneural-like precursor glioma
…, YK Cheng, JT Huse, M Squatrito, K Helmy, N Charles… - Cancer cell, 2014 - cell.com
To understand the relationships between the non-GCIMP glioblastoma (GBM) subgroups, we
performed mathematical modeling to predict the temporal sequence of driver events during …
performed mathematical modeling to predict the temporal sequence of driver events during …
Carbon cycle confidence and uncertainty: Exploring variation among soil biogeochemical models
Emerging insights into factors responsible for soil organic matter stabilization and decomposition
are being applied in a variety of contexts, but new tools are needed to facilitate the …
are being applied in a variety of contexts, but new tools are needed to facilitate the …