Twenty-eight patients (12 men with prostate cancer, 16 women with breast cancer) were
included in a phase II trial to evaluate the efficacy of 186 Re-hydroxyethylidene diphosphonate (…

In Lille (a large city in northern France), the municipal council has set up an Health Observatory
in order to provide health information on the city's population, promote educational …

ATG4B stimulates autophagy by promoting autophagosome formation through reversible
modification of ATG8. We identify ATG4B as a substrate of mammalian sterile20-like kinase (…

Aberrant cell proliferation is a hallmark of cancer, including glioblastoma (GBM). Here we
report that protein arginine methyltransferase (PRMT) 6 activity is required for the proliferation, …

We have profiled promoter DNA methylation alterations in 272 glioblastoma tumors in the
context of The Cancer Genome Atlas (TCGA). We found that a distinct subset of samples …

We leveraged IDH wild-type glioblastomas, derivative neurospheres, and single-cell gene
expression profiles to define three tumor-intrinsic transcriptional subtypes designated as …

Glioblastoma stem cells (GSCs) are implicated in tumor neovascularization, invasiveness,
and therapeutic resistance. To illuminate mechanisms governing these hallmark features, we …

A first research development progress report of the Chromosome 19 Consortium with members
from Sweden, Norway, Spain, United States, China and India, a part of the Chromosome-…

To understand the relationships between the non-GCIMP glioblastoma (GBM) subgroups, we
performed mathematical modeling to predict the temporal sequence of driver events during …

Emerging insights into factors responsible for soil organic matter stabilization and decomposition
are being applied in a variety of contexts, but new tools are needed to facilitate the …