Variations of dynamic contrast-enhanced magnetic resonance imaging in evaluation of breast cancer therapy response: a multicenter data analysis challenge

…, A Fedorov, A Tudorica, SN Gupta, CM Laymon… - Translational …, 2014 - Elsevier
Pharmacokinetic analysis of dynamic contrast-enhanced magnetic resonance imaging (DCE-MRI)
time-course data allows estimation of quantitative parameters such as K trans (rate …

Infection Dynamics and Response to Chemotherapy in a Rabbit Model of Tuberculosis using [18F]2-Fluoro-Deoxy-d-Glucose Positron Emission Tomography and …

…, RJ Kastenmayer, CM Laymon… - Antimicrobial agents …, 2012 - Am Soc Microbiol
With a host of new antitubercular chemotherapeutics in development, methods to assess
the activity of these agents beyond mouse efficacy are needed to prioritize combinations for …

The impact of arterial input function determination variations on prostate dynamic contrast-enhanced magnetic resonance imaging pharmacokinetic modeling: a …

…, J Kalpathy-Cramer, JM Mountz, CM Laymon, M Muzi… - Tomography, 2016 - mdpi.com
Pharmacokinetic analysis of dynamic contrast-enhanced (DCE) MRI data allows estimation
of quantitative imaging biomarkers such as K trans (rate constant for plasma/interstitium …

Direct comparison of the tau PET tracers 18F-flortaucipir and 18F-MK-6240 in human subjects

…, JM Mountz, TA Pascoal, CM Laymon… - Journal of Nuclear …, 2022 - Soc Nuclear Med
Tau PET tracers exhibit varying levels of specific signal and distinct off-target binding patterns
that are more diverse than amyloid PET tracers. This study compared 2 frequently used tau …

[HTML][HTML] A multi-scanner neuroimaging data harmonization using RAVEL and ComBat

…, G Ahmad, EE O'Connor, J Muschelli, CM Laymon… - Neuroimage, 2021 - Elsevier
Modern neuroimaging studies frequently combine data collected from multiple scanners and
experimental conditions. Such data often contain substantial technical variability associated …

Relative 11C-PiB delivery as a proxy of relative CBF: quantitative evaluation using single-session 15O-water and 11C-PiB PET

…, BL Rosario, W Mowrey, CM Laymon… - Journal of Nuclear …, 2015 - Soc Nuclear Med
The primary goal of this study was to assess the suitability of 11 C-Pittsburgh compound B (
11 C-PiB) blood–brain barrier delivery (K 1 ) and relative delivery (R 1 ) parameters as …

[HTML][HTML] Striatal dopamine supports reward expectation and learning: a simultaneous PET/fMRI study

FJ Calabro, DF Montez, B Larsen, CM Laymon… - NeuroImage, 2023 - Elsevier
Converging evidence from both human neuroimaging and animal studies has supported a
model of mesolimbic processing underlying reward learning behaviors, based on the …

Combined VLA-4–targeted radionuclide therapy and immunotherapy in a mouse model of melanoma

…, RJ Fecek, KPL Fabian, CM Laymon… - Journal of Nuclear …, 2018 - Soc Nuclear Med
Very late antigen-4 (VLA-4; also known as integrin α 4 β 1 ) is expressed at high levels in
aggressive and metastatic melanoma tumors and may provide an ideal target for imaging and …

Errors in quantitative image analysis due to platform-dependent image scaling

…, R Kikinis, TT Liu, M Muzi, MJ Oborski, CM Laymon… - Translational …, 2014 - Elsevier
PURPOSE: To evaluate the ability of various software (SW) tools used for quantitative
image analysis to properly account for source-specific image scaling employed by magnetic …

Pet/ct artifacts

TM Blodgett, AS Mehta, AS Mehta, CM Laymon… - Clinical imaging, 2011 - Elsevier
There are several artifacts encountered in positron emission tomography/computed tomographic
(PET/CT) imaging, including attenuation correction (AC) artifacts associated with using …