User profiles for Charles H. Cunningham
Charles H CunninghamUniversity of Toronto, Sunnybrook Health Sciences Centre Verified email at utoronto.ca Cited by 7992 |
[HTML][HTML] Analysis of cancer metabolism by imaging hyperpolarized nuclei: prospects for translation to clinical research
A major challenge in cancer biology is to monitor and understand cancer metabolism in vivo
with the goal of improved diagnosis and perhaps therapy. Because of the complexity of …
with the goal of improved diagnosis and perhaps therapy. Because of the complexity of …
Hyperpolarized 13C Lactate, Pyruvate, and Alanine: Noninvasive Biomarkers for Prostate Cancer Detection and Grading
MJ Albers, R Bok, AP Chen, CH Cunningham… - Cancer research, 2008 - AACR
An extraordinary new technique using hyperpolarized 13 C-labeled pyruvate and taking
advantage of increased glycolysis in cancer has the potential to improve the way magnetic …
advantage of increased glycolysis in cancer has the potential to improve the way magnetic …
Positive contrast magnetic resonance imaging of cells labeled with magnetic nanoparticles
CH Cunningham, T Arai, PC Yang… - … in Medicine: An …, 2005 - Wiley Online Library
Contrast agents incorporating superparamagnetic iron‐oxide nanoparticles have shown
promise as a means to visualize labeled cells using MRI. Labeled cells cause significant signal …
promise as a means to visualize labeled cells using MRI. Labeled cells cause significant signal …
Saturated double‐angle method for rapid B1+ mapping
CH Cunningham, JM Pauly… - Magnetic Resonance in …, 2006 - Wiley Online Library
For in vivo magnetic resonance imaging at high field (≥3 T) it is essential to consider the
homogeneity of the active B 1 field (B 1 +), particularly if surface coils are used for RF …
homogeneity of the active B 1 field (B 1 +), particularly if surface coils are used for RF …
[HTML][HTML] Hyperpolarized 13C MRI: path to clinical translation in oncology
This white paper discusses prospects for advancing hyperpolarization technology to better
understand cancer metabolism, identify current obstacles to HP (hyperpolarized) 13 C …
understand cancer metabolism, identify current obstacles to HP (hyperpolarized) 13 C …
Hyperpolarized 13C Metabolic MRI of the Human Heart: Initial Experience
Rationale: Altered cardiac energetics is known to play an important role in the progression
toward heart failure. A noninvasive method for imaging metabolic markers that could be used …
toward heart failure. A noninvasive method for imaging metabolic markers that could be used …
DWI of the spinal cord with reduced FOV single‐shot EPI
EU Saritas, CH Cunningham, JH Lee… - … in Medicine: An …, 2008 - Wiley Online Library
Single‐shot echo‐planar imaging (ss‐EPI) has not been used widely for diffusion‐weighted
imaging (DWI) of the spinal cord, because of the magnetic field inhomogeneities around the …
imaging (DWI) of the spinal cord, because of the magnetic field inhomogeneities around the …
Variable‐rate selective excitation for rapid MRI sequences
BA Hargreaves, CH Cunningham… - … in Medicine: An …, 2004 - Wiley Online Library
Balanced steady‐state free precession (SSFP) imaging sequences require short repetition
times (TRs) to avoid off‐resonance artifacts. The use of slab‐selective excitations is common, …
times (TRs) to avoid off‐resonance artifacts. The use of slab‐selective excitations is common, …
Hyperpolarized C‐13 spectroscopic imaging of the TRAMP mouse at 3T—initial experience
AP Chen, MJ Albers, CH Cunningham… - … in Medicine: An …, 2007 - Wiley Online Library
The transgenic adenocarcinoma of mouse prostate (TRAMP) mouse is a well‐studied
murine model of prostate cancer with histopathology and disease progression that mimic the …
murine model of prostate cancer with histopathology and disease progression that mimic the …
Temporal stability of adaptive 3D radial MRI using multidimensional golden means
…, EA Ramsay, CH Cunningham… - … in Medicine: An …, 2009 - Wiley Online Library
Breast tumor diagnosis requires both high spatial resolution to obtain information about tumor
morphology and high temporal resolution to probe the kinetics of contrast uptake. Adaptive …
morphology and high temporal resolution to probe the kinetics of contrast uptake. Adaptive …