OBJECTIVE: To evaluate prospectively the efficacy and safety of 1 intravitreal injection of 4
mg of triamcinolone acetonide for refractory diffuse diabetic macular edema. DESIGN: …

purpose. To develop a population model capable of describing the profile of the effect of
intravitreal triamcinolone acetonide in the treatment of diabetic diffuse macular edema. methods…

To determine whether informed consent in a therapeutic trial modifies the analgesic effect of
naproxen and placebo, we conducted a prospective, randomised, single dose, placebo-…

BACKGROUND AND OBJECTIVES: Paracetamol (acetaminophen) has occasionally been
reported to interact with warfarin. The primary end-point of this study was to investigate …

WHAT IT IS ALREADY KNOW ABOUT THIS SUBJECT • Amiodarone is a highly effective
antiarrhythmic drug, but is limited in practice by its adverse effects, which are frequent on long‐…

High mean levels of D-dimers (DD), markers of fibrin product and degradation, have been
reported in patients with atrial fibrillation. In order to determine the predictive value of DD, 125 …

SIR—A microemulsion formulation of cyclosporin (Neoral) is a bioavailable form of this potent
immunosuppressive drug. Absorption of the parent compound is less affected by food, and …

Methods All subjects underwent a preliminary general clinical and neurologic examination.
The following investigations were then performed: 1. Quantitative measurement of CBF by …

Calcium channel antagonists (CCAs) may either be divided into the dihydropyridines (eg
amlodipine, felodipine, isradipine, lacidipine, nilvadipine, nifedipine, nicardipine etc.), the …

The protease inhibitor saquinavir was administered to 100 human immunodeficiency virus
type 1 (HIV-1)-infected patients as a single 600-mg oral dose (hard gelatin capsules) with a …