[HTML][HTML] Duration and key determinants of infectious virus shedding in hospitalized patients with coronavirus disease-2019 (COVID-19)

…, S van Boheemen, JC Voermans, CAB Boucher… - Nature …, 2021 - nature.com
Key questions in COVID-19 are the duration and determinants of infectious virus shedding.
Here, we report that infectious virus shedding is detected by virus cultures in 23 of the 129 …

[HTML][HTML] Drug resistance mutations for surveillance of transmitted HIV-1 drug-resistance: 2009 update

…, AM Vandamme, P Sandstrom, CAB Boucher… - PloS one, 2009 - journals.plos.org
Programs that monitor local, national, and regional levels of transmitted HIV-1 drug resistance
inform treatment guidelines and provide feedback on the success of HIV-1 treatment and …

Ordered accumulation of mutations in HIV protease confers resistance to ritonavir

…, A Hsu, GR Granneman, DD Ho, CAB Boucher… - Nature medicine, 1996 - nature.com
Abstract Analysis of the HIV protease gene from the plasma of HIV–infected patients
revealed substitutions at nine different codons selected in response to monotherapy with the …

Combining clinical and thallium data optimizes preoperative assessment of cardiac risk before major vascular surgery

…, HW Strauss, TE Guiney, CA Boucher - Annals of internal …, 1989 - acpjournals.org
Study Objective: To determine whether clinical markers and preoperative dipyridamole-thallium
imaging are both useful in predicting ischemic events after vascular surgery. Design: …

[PDF][PDF] Technetium-99m hexakis 2-methoxyisobutyl isonitrile: human biodistribution, dosimetry, safety, and preliminary comparison to thallium-201 for myocardial …

…, GA Beller, HW Strauss, CA Boucher… - Journal of Nuclear …, 1989 - Soc Nuclear Med
Boucher, Michel Picard, B.Leonard Holman, R. Fridrich, Eugemo Inglese, Bernard
Delaloye, … MassachusettsGeneral Hospital,Boston,Mas sachusetts, Investigators: Charles …

Pathogenesis and transmission of swine-origin 2009 A (H1N1) influenza virus in ferrets

…, TM Bestebroer, D van de Vijver, CA Boucher… - Science, 2009 - science.org
The swine-origin A(H1N1) influenza virus that has emerged in humans in early 2009 has
raised concerns about pandemic developments. In a ferret pathogenesis and transmission …

[HTML][HTML] A short-term study of the safety, pharmacokinetics, and efficacy of ritonavir, an inhibitor of HIV-1 protease

…, A Hsu, JM Valdes, CAB Boucher… - … England Journal of …, 1995 - Mass Medical Soc
Background Reverse-transcriptase inhibitors have only moderate clinical efficacy against
the human immunodeficiency virus type 1 (HIV-1). Ritonavir is an inhibitor of HIV-1 protease …

T-cell division in human immunodeficiency virus (HIV)-1 infection is mainly due to immune activation: a longitudinal analysis in patients before and during highly active …

…, SA Otto, JCC Borleffs, CAB Boucher… - Blood, The Journal …, 2000 - ashpublications.org
In human immunodeficiency virus (HIV)-1 infection, highly increased T-cell turnover was
proposed to cause exhaustion of lymphocyte production and consequently development of AIDS…

An automated genotyping system for analysis of HIV-1 and other microbial sequences

…, AMJ Wensing, DA Van De Vijver, CA Boucher… - …, 2005 - academic.oup.com
Motivation: Genetic analysis of HIV-1 is important not only for vaccine development, but also
to guide treatment strategies, track the emergence of new viral variants and ensure that …

Rapid changes in human immunodeficiency virus type 1 RNA load and appearance of drug-resistant virus populations in persons treated with lamivudine (3TC)

…, S Kwok, J Sninsky, CAB Boucher - Journal of Infectious …, 1995 - academic.oup.com
The effect of the appearance of drug-resistant human immunodeficiency virus type 1 (HIV-1)
on viral RNA load was studied in patients treated with the reverse transcriptase inhibitor …