Efficacy of dilute betadine solution irrigation in the prevention of postoperative infection of spinal surgery

MT Cheng, MC Chang, ST Wang, WK Yu, CL Liu… - 2005 - journals.lww.com
Study Design. Prospective, single-blinded, randomized study. Objectives. To evaluate the
efficacy of dilute betadine irrigation of spinal surgical wounds in prevention of postoperative …

The anti-apoptotic role of interleukin-6 in human cervical cancer is mediated by up-regulation of Mcl-1 through a PI 3-K/Akt pathway

LH Wei, ML Kuo, CA Chen, CH Chou, WF Cheng… - Oncogene, 2001 - nature.com
Interleukin-6 (IL-6), a multifunctional cytokine, has recently been implicated in human cervical
cancer, though the mechanism remains elusive. This study demonstrates that the anti-…

A Fourier method for the fractional diffusion equation describing sub-diffusion

CM Chen, F Liu, I Turner, V Anh - Journal of Computational Physics, 2007 - Elsevier
In this paper, a fractional partial differential equation (FPDE) describing sub-diffusion is
considered. An implicit difference approximation scheme (IDAS) for solving a FPDE is presented. …

The effects of Taiwan's National Health Insurance on access and health status of the elderly

L Chen, W Yip, MC Chang, HS Lin, SD Lee… - Health …, 2007 - Wiley Online Library
The primary objective of this paper is to evaluate the impact of Taiwan's National Health
Insurance program (NHI), established in 1995, on improving elderly access to care and health …

[HTML][HTML] Interleukin-6 inhibits transforming growth factor-β-induced apoptosis through the phosphatidylinositol 3-kinase/Akt and signal transducers and activators of …

RH Chen, MC Chang, YH Su, YT Tsai… - Journal of Biological …, 1999 - ASBMB
The multifunctional cytokine interleukin-6 (IL-6) regulates growth and differentiation of many
cell types and induces production of acute-phase proteins in hepatocytes. Here we report …

Mesothelin enhances invasion of ovarian cancer by inducing MMP-7 through MAPK/ERK and JNK pathways

…, CA Chen, PJ Chen, YC Chiang, YL Chen… - Biochemical …, 2012 - portlandpress.com
… Chi-An Chen and Pao-Jen Chen participated in the interpretation of experimental results
and discussion. Ying-Cheng Chiang also advised on and evaluated the animal experiments. Yu…

[HTML][HTML] High mesothelin correlates with chemoresistance and poor survival in epithelial ovarian carcinoma

…, YC Chiang, YL Chen, CY Hsieh, CA Chen - British journal of …, 2009 - nature.com
The objective of this paper is to investigate the mesothelin expression level to the
clinicopathological features, chemoresponse, and to the outcome of patients with epithelial ovarian …

Numerical schemes with high spatial accuracy for a variable-order anomalous subdiffusion equation

CM Chen, F Liu, V Anh, I Turner - SIAM Journal on Scientific Computing, 2010 - SIAM
In this paper, we consider a variable-order anomalous subdiffusion equation. A numerical
scheme with first order temporal accuracy and fourth order spatial accuracy for the equation is …

Metronomic chemotherapy and immunotherapy in cancer treatment

YL Chen, MC Chang, WF Cheng - Cancer Letters, 2017 - Elsevier
Systemic chemotherapy given at maximum tolerated doses (MTD) has been the mainstay of
cancer treatment for more than half a century. In some chemosensitive diseases such as …

[HTML][HTML] Serous ovarian carcinoma patients with high alpha-folate receptor had reducing survival and cytotoxic chemo-response

…, YC Chiang, HW Lin, CA Chen, CY Hsieh, WF Cheng - Molecular …, 2012 - Elsevier
The alpha-folate receptor (α-FR) is highly-expressed in various non-mucinous tumors of
epithelial origin, including ovarian carcinoma. The aim of this study was to investigate the …