A clinically applicable integrative molecular classification of meningiomas

…, O Singh, S Karimi, RI Corona, LY Liu, CY Chen… - Nature, 2021 - nature.com
Meningiomas are the most common primary intracranial tumour in adults 1 . Patients with
symptoms are generally treated with surgery as there are no effective medical therapies. The …

[PDF][PDF] An improved method to calculate cerebral metabolic rates of glucose using PET

RL Phillips, CY Chen, DF Wong… - Journal of Nuclear …, 1995 - Soc Nuclear Med
2 match the activity of two different samples of Cpn (t).* Values of CMRglc calculated by
numerically integrating the normalized population average curve of Cp (t) correlate well with …

[HTML][HTML] Mass spectrometric analyses of phospholipids in the S334ter-3 rat model of retinal degeneration

CY Chen, BL Lam, SK Bhattacharya - Molecular vision, 2014 - ncbi.nlm.nih.gov
Purpose The purpose of this study was to profile the endogenous phospholipid species in
the retinal tissue of the S334ter-3 rat model of retinal degeneration. Retinal tissue was …

Genome-wide transcriptional profiling linked to social class in asthma

E Chen, GE Miller, HA Walker, JM Arevalo, CY Sung… - Thorax, 2009 - thorax.bmj.com
Objectives: Low socioeconomic status (SES) is one of the most robust social factors
associated with disease morbidity, including more severe asthma in childhood. However, our …

Long-term outcomes of 176 patients with X-linked hyper-IgM syndrome treated with or without hematopoietic cell transplantation

…, CY Kuo, CC Dvorak, I Meyts, K Chen… - Journal of allergy and …, 2017 - Elsevier
Background X-linked hyper-IgM syndrome (XHIGM) is a primary immunodeficiency with high
morbidity and mortality compared with those seen in healthy subjects. Hematopoietic cell …

Scaffold-mediated CRISPR-Cas9 delivery system for acute myeloid leukemia therapy

TC Ho, HS Kim, Y Chen, Y Li, MW LaMere, C Chen… - Science …, 2021 - science.org
Leukemia stem cells (LSCs) sustain the disease and contribute to relapse in acute myeloid
leukemia (AML). Therapies that ablate LSCs may increase the chance of eliminating this …

[HTML][HTML] Profound T cell Lymphopenia associated with prenatal exposure to purine antagonists detected by TREC newborn screening

…, P Slev, JF Bohnsack, K Chen - The journal of allergy …, 2017 - ncbi.nlm.nih.gov
Recognition of non-SCID and secondary causes of T cell lymphopenia detected by TREC
newborn screening is important in directing subsequent care and identifying those who would …

DNA vaccine protection against SARS-CoV-2 in rhesus macaques

…, C Atyeo, S Fischinger, JS Burke, MD Slein, Y Chen… - Science, 2020 - science.org
The global coronavirus disease 2019 (COVID-19) pandemic caused by severe acute respiratory
syndrome coronavirus 2 (SARS-CoV-2) has made the development of a vaccine a top …

New genetic loci implicated in fasting glucose homeostasis and their impact on type 2 diabetes risk

…, E Brunner, SJ Bumpstead, G Charpentier, YDI Chen… - Nature …, 2010 - nature.com
Levels of circulating glucose are tightly regulated. To identify new loci influencing glycemic
traits, we performed meta-analyses of 21 genome-wide association studies informative for …

Phylogeography of Anguilla marmorata (Teleostei: Anguilliformes) from the eastern Caroline Islands

S Donovan, F Pezold, Y Chen, B Lynch - Ichthyological research, 2012 - Springer
… Kosrae and Pohnpei are two eastern Caroline Islands surveyed in this study (black circles).
The other 13 locations (open circles) were analyzed in Minegishi et al. (2008) …