Data-driven subgroups of type 2 diabetes, metabolic response, and renal risk profile after bariatric surgery: a retrospective cohort study

…, H Verkindt, TBZ Petry, C Marciniak… - The Lancet Diabetes & …, 2022 - thelancet.com
Background A novel data-driven classification of type 2 diabetes has been proposed to
personalise anti-diabetic treatment according to phenotype. One subgroup, severe insulin-…

Doxorubicin-induced cardiac dysfunction is attenuated by ciclosporin treatment in mice through improvements in mitochondrial bioenergetics

X Marechal, D Montaigne, C Marciniak… - Clinical …, 2011 - portlandpress.com
We tested whether inhibition of mitochondrial membrane potential dissipation by CsA (ciclosporin
A) would prevent doxorubicin-induced myocardial and mitochondrial dysfunction. …

[HTML][HTML] Carbon monoxide improves cardiac function and mitochondrial population quality in a mouse model of metabolic syndrome

S Lancel, D Montaigne, X Marechal, C Marciniak… - 2012 - journals.plos.org
Aims Metabolic syndrome induces cardiac dysfunction associated with mitochondria
abnormalities. As low levels of carbon monoxide (CO) may improve myocardial and mitochondrial …

[HTML][HTML] Impact of lymph node dissection on postoperative complications of total thyroidectomy in patients with thyroid carcinoma

G Baud, A Jannin, C Marciniak, B Chevalier, C Do Cao… - Cancers, 2022 - mdpi.com
Simple Summary Thyroid cancers are the most common endocrine cancers and their
incidence has increased significantly in recent decades worldwide. Total thyroidectomy is …

[HTML][HTML] Cardiac contractile function and mitochondrial respiration in diabetes-related mouse models

C Marciniak, X Marechal, D Montaigne… - Cardiovascular …, 2014 - Springer
Background Pathophysiological processes underlying diabetic-related cardiomyopathies are
complex. Mitochondria dysfunction is often described as a cause of cardiac impairment but …

Risk factors of redo surgery after unilateral focused parathyroidectomy: conclusions from a comprehensive nationwide database of 13,247 interventions over 6 years

G Donatini, C Marciniak, X Lenne, G Clément… - Annals of …, 2020 - journals.lww.com
Background: Surgical removal of hyperfunctional parathyroid gland is the definitive treatment
for primary hyperparathyroidism (pHPT). Postoperative follow-up shows variability in …

[PDF][PDF] Oral metformin transiently lowers post-prandial glucose response by reducing the apical expression of sodium-glucose co-transporter 1 in enterocytes

…, F Auger, V Touche, T Hubert, J Thevenet, C Marciniak… - Iscience, 2023 - cell.com
Metformin (MET) is the most prescribed antidiabetic drug, but its mechanisms of action remain
elusive. Recent data point to the gut as MET's primary target. Here, we explored the effect …

Adrenalectomy risk score: an original preoperative surgical scoring system to reduce mortality and morbidity after adrenalectomy

R Caiazzo, C Marciniak, X Lenne, G Clément… - Annals of …, 2019 - journals.lww.com
Objective: To explore the determinants of postoperative outcomes of adrenal surgery in
order to build a proposition for healthcare improvement. Summary of Background Data: …

Partial versus total thyroidectomy: what influences most surgeons' decision? Analysis of a nationwide cohort of 375,810 patients over 10 years

C Marciniak, X Lenne, G Clément, A Bruandet… - Annals of …, 2021 - journals.lww.com
National and international guidelines about thyroid surgery seem to be moving more and
more towards less radical surgical procedures but everyday practice does not seem to always …

Caspase-dependent protein phosphatase 2A activation contributes to endotoxin-induced cardiomyocyte contractile dysfunction

…, D Montaigne, X Maréchal, C Marciniak… - Critical care …, 2010 - journals.lww.com
Objective: Several studies report calcium mishandling, sarcomere disarray, and caspase
activation during heart failure. Although active caspases have been shown to cleave …