[HTML][HTML] Brain inflammation is induced by co-morbidities and risk factors for stroke
…, R Hinz, A Gerhard, A Vail, C Prenant… - Brain, behavior, and …, 2011 - Elsevier
Chronic systemic inflammatory conditions, such as atherosclerosis, diabetes and obesity
are associated with increased risk of stroke, which suggests that systemic inflammation may …
are associated with increased risk of stroke, which suggests that systemic inflammation may …
Synthesis of N‐(11C) methyl, N‐(methyl‐1 propyl), (chloro‐2 phenyl)‐1 isoquinoleine carboxamide‐3 (PK 11195): A new ligand for peripheral benzodiazepine …
…, D Comar, M Maziere, C Prenant… - Journal of Labelled …, 1984 - Wiley Online Library
… was the ( 11 C) methyl iodide obtained from nuclear reaction 14 N (p, α) 11 C via 11 CO 2
… that sterile and isotonic injectable solution of ( 11 C) MPCI ready for use may be obtained, in …
… that sterile and isotonic injectable solution of ( 11 C) MPCI ready for use may be obtained, in …
A review of approaches to 18F radiolabelling affinity peptides and proteins
…, M Fairclough, J Grigg, C Prenant… - Journal of Labelled …, 2019 - Wiley Online Library
… It has, however, been found that its electronic properties can lead to improved pharmacological
characteristics and the strength of the C―F bond (112 kcal/mol), in comparison to the C―…
characteristics and the strength of the C―F bond (112 kcal/mol), in comparison to the C―…
Synthesis of ethyl 8-fluoro-5, 6-dihydro5-[11C] methyl-6-oxo-4H-imidazo [1, 5-a][1, 4] benzodiazepine-3-carboxylate (RO 15.1788-11C): a specific radioligand for the …
M Maziere, P Hantraye, C Prenant, J Sastre… - The International journal …, 1984 - Elsevier
… This is separated by distillation and passage of the vapour through a solution of hydriodic
acid at 130C and gives about I Ci (37 GBq) of [t~C]methyl iodide. The latter is carried by a …
acid at 130C and gives about I Ci (37 GBq) of [t~C]methyl iodide. The latter is carried by a …
[PDF][PDF] PET study of carbon-11-PK 11195 binding to peripheral type benzodiazepine sites in glioblastoma: a case report
… , has been labeled with ~'C (7), and the labeled … C-PK 1 t 195 uptake that is increased
two-tbid in the tumor with respect to the normal contralateral gray matter. About 30% of tumoral I~C-…
two-tbid in the tumor with respect to the normal contralateral gray matter. About 30% of tumoral I~C-…
Peripheral-type benzodiazepine receptors in the living heart characterized by positron emission tomography.
…, A Syrota, C Crouzel, JM Valois, C Prenant… - Circulation, 1986 - Am Heart Assoc
… The specificity of 1 'C-PK 11195 binding to canine heart was … C-PK 11195 synthesis
method has been described elsewhere.'8 'CO2 was produced in a medical cyclotron and I"C…
method has been described elsewhere.'8 'CO2 was produced in a medical cyclotron and I"C…
Microfluidic reactor for the radiosynthesis of PET radiotracers
JM Gillies, C Prenant, GN Chimon, GJ Smethurst… - Applied Radiation and …, 2006 - Elsevier
Here we show the first application of a microfabricated reaction system to PET radiochemistry,
we term “microfluidic PET”. The short half-life of the positron emitting isotopes and the …
we term “microfluidic PET”. The short half-life of the positron emitting isotopes and the …
Automated synthesis of 11C-labelled radiopharmaceuticals: imipramine, chlorpromazine, nicotine and methionine
G Berger, M Maziere, R Knipper, C Prenant… - The International Journal …, 1979 - Elsevier
This article describes a method by which about a hundred mCi of different radiopharmaceuticals
(imipramine, chlorpromazine, nicotine or methionine) may be prepared in 30–35 min …
(imipramine, chlorpromazine, nicotine or methionine) may be prepared in 30–35 min …
[HTML][HTML] [18F]DPA-714: Direct Comparison with [11C]PK11195 in a Model of Cerebral Ischemia in Rats
… ]DPA-714 rather than [ 11 C]PK11195 since we show here that the uptake in the contralateral
healthy tissue (ie non-specific binding) is lower than for [ 11 C]PK11195 hence leading to a …
healthy tissue (ie non-specific binding) is lower than for [ 11 C]PK11195 hence leading to a …
Regional Specific Binding of [11C]RO 15 1788 to Central Type Benzodiazepine Receptors in Human Brain: Quantitative Evaluation by PET
…, Y Samson, C Chavoix, C Prenant… - Journal of Cerebral …, 1988 - journals.sagepub.com
… C–RO 15 1788 and positron emission tomography (PET). The brain regional distribution of
the tracer in eight control studies performed after injection of trace doses of 11 C-… bound 11 C-…
the tracer in eight control studies performed after injection of trace doses of 11 C-… bound 11 C-…