OBJECTIVES: Irritable bowel syndrome (IBS) is a common gastrointestinal condition with a
heterogeneous pathophysiology. An altered gut microbiome has been identified in some IBS …

… Immunohistochemical studies have demonstrated that CCK-8 administration evokes an
increase in the percentage of c-Fos—positive pancreatic neurons containing choline …

… The α subunit then dissociates from the βγ subunit to activate phospholipase C-β2 (PLCβ2),
leading to 1,4,5-inositol triphosphate-mediated release of intracellular Ca 2 + and …

Over the past twenty years, thousands of physicians have come to depend on Yamada’s
Textbook of Gastroenterology. Its encyclopaedic discussion of the basic science underlying …

Background. Patients with scleroderma may have abnormal motility of the small intestine,
with pseudoobstruction and bacterial overgrowth. Standard stimulatory agents are often …

Ginger has long been used as an alternative medication to prevent motion sickness. The
mechanism of its action, however, is unknown. We hypothesize that ginger ameliorates the …

… , NJ) using the following protocol: 50C for 2 minutes, 95C for 10 minutes, followed by 40
cycles of 95C for 15 seconds, 60C for 60 seconds, and hold at 37C. To detect bacterial signal, 2 …

1 The vagus nerve conveys primary afferent information produced by a meal to the brainstem.
Serotonin (5‐HT), which abounds in intestinal enterochromaffin cells, is released in …

The objective of this study was to examine the effect of serum glucose concentration on
interdigestive gastrointestinal motility and plasma motilin levels in humans. Motility studies were …

Background/Aims : Antral hypomotility and gastric dysrhythmias occur in diabetic
gastroparesis. This study tested the hypothesis that acute hyperglycemia suppresses fed antral …