Background— Matrix metalloproteinases (MMPs) are enzymes involved in the proteolytic
degradation of extracellular matrix. They play an important role in several disease processes, …

The transcriptional activation mediated by cAMP-response element (CRE) and transcription
factors of the CRE-binding protein (CREB)/CRE modulator (CREM) family represents an …

Aim: Evaluate the clinical benefit of external beam radiotherapy (RTx) for locally invasive
thyroid carcinoma with follicular cell differentiation (DTC). Patients, methods: The Multicentre …

Aims Clinical observations in patients with long QT syndrome carrying sodium channel
mutations (LQT3) suggest that bradycardia caused by parasympathetic stimulation may provoke …

Purpose: Restoration of iodine incorporation (redifferentiation) by MAPK inhibition was achieved
in previously radioiodine-refractory, unresectable thyroid carcinoma (RR-TC). However, …

Objective: In this retrospective cohort study, we describe the clinical presentation and workup
of parathyroid carcinoma (PC) and determine its clinical prognostic parameters. Primary …

Background: Despite an excellent survival rate, impairments are recognized in the quality of
life and emotional well-being of differentiated thyroid cancer (DTC) survivors. Predictors for …

Matrix metalloproteinases (MMPs) are zinc‐ and calcium‐dependent endopeptidases.
Representing a subfamily of the metzincin superfamily, MMPs are involved in the proteolytic …

Purpose Given the large number of patients with thyroid nodules, improvement of the specificity
of current ultrasound-based thyroid nodule classification systems (ATA, EU-TIRADS, and …

Introduction Efficient therapy of recurrent differentiated thyroid cancer (DTC) is dependent
on precise molecular imaging techniques targeting the human sodium iodide symporter (hNIS)…