The Tabula Sapiens: A multiple-organ, single-cell transcriptomic atlas of humans
…, M Tan, J Yan, GR Bean, V Charu, E Forgó, BA Martin… - Science, 2022 - science.org
Molecular characterization of cell types using single-cell transcriptome sequencing is
revolutionizing cell biology and enabling new insights into the physiology of human organs. We …
revolutionizing cell biology and enabling new insights into the physiology of human organs. We …
Pharmacokinetics and efficacy of a potential smallpox therapeutic, brincidofovir, in a lethal monkeypox virus animal model
…, CM Hughes, Y Nakazawa, C Kling, BE Martin… - MSphere, 2021 - Am Soc Microbiol
Smallpox, caused by Variola virus (VARV), was eradicated in 1980; however, VARV bioterrorist
threats still exist, necessitating readily available therapeutics. Current preparedness …
threats still exist, necessitating readily available therapeutics. Current preparedness …
[HTML][HTML] Impact of a deep learning assistant on the histopathologic classification of liver cancer
Artificial intelligence (AI) algorithms continue to rival human performance on a variety of clinical
tasks, while their actual impact on human diagnosticians, when incorporated into clinical …
tasks, while their actual impact on human diagnosticians, when incorporated into clinical …
Randomized study of temozolomide or temozolomide and capecitabine in patients with advanced pancreatic neuroendocrine tumors (ECOG-ACRIN E2211)
…, TA Longacre, CJ Suarez, BA Martin… - Journal of Clinical …, 2023 - ascopubs.org
PURPOSE Patients with advanced pancreatic neuroendocrine tumors (NETs) have few
treatment options that yield objective responses. Retrospective and small prospective studies …
treatment options that yield objective responses. Retrospective and small prospective studies …
ORAL SHEDDING OF MARBURG VIRUS IN EXPERIMENTALLY INFECTED EGYPTIAN FRUIT BATS (ROUSETTUS AEGYPTIACUS)
…, JAD Coleman-McCray, BE Martin… - Journal of wildlife …, 2015 - meridian.allenpress.com
Marburg virus (Marburg marburgvirus; MARV) causes sporadic outbreaks of Marburg
hemorrhagic fever (MHF) in Africa. The Egyptian fruit bat (Rousettus aegyptiacus) has been …
hemorrhagic fever (MHF) in Africa. The Egyptian fruit bat (Rousettus aegyptiacus) has been …
Determination of tumor margins with surgical specimen mapping using near-infrared fluorescence
…, NT Teraphongphom, NS van den Berg, BA Martin… - Cancer research, 2018 - AACR
For many solid tumors, surgical resection remains the gold standard and tumor-involved
margins are associated with poor clinical outcomes. Near-infrared (NIR) fluorescence imaging …
margins are associated with poor clinical outcomes. Near-infrared (NIR) fluorescence imaging …
[HTML][HTML] Modelling filovirus maintenance in nature by experimental transmission of Marburg virus between Egyptian rousette bats
…, LS Uebelhoer, JR Spengler, BE Martin… - Nature …, 2017 - nature.com
The Egyptian rousette bat (ERB) is a natural reservoir host for Marburg virus (MARV);
however, the mechanisms by which MARV is transmitted bat-to-bat and to other animals are …
however, the mechanisms by which MARV is transmitted bat-to-bat and to other animals are …
Origins and clonal convergence of gastrointestinal IgE+ B cells in human peanut allergy
RA Hoh, SA Joshi, JY Lee, BA Martin, S Varma… - Science …, 2020 - science.org
B cells in human food allergy have been studied predominantly in the blood. Little is known
about IgE + B cells or plasma cells in tissues exposed to dietary antigens. We characterized …
about IgE + B cells or plasma cells in tissues exposed to dietary antigens. We characterized …
[HTML][HTML] Co-administered antibody improves penetration of antibody–dye conjugate into human cancers with implications for antibody–drug conjugates
Poor tissue penetration remains a major challenge for antibody-based therapeutics of solid
tumors, but proper dosing can improve the tissue penetration and thus therapeutic efficacy of …
tumors, but proper dosing can improve the tissue penetration and thus therapeutic efficacy of …
The clinical application of fluorescence-guided surgery in head and neck cancer
…, S Fakurnejad, A Birkeland, BA Martin… - Journal of Nuclear …, 2019 - Soc Nuclear Med
Although surgical resection has been the primary treatment modality of solid tumors for
decades, surgeons still rely on visual cues and palpation to delineate healthy from cancerous …
decades, surgeons still rely on visual cues and palpation to delineate healthy from cancerous …