Dynamic SPECT measurement of absolute myocardial blood flow in a porcine model

…, R Klein, J Lockwood, B Marvin… - Journal of Nuclear …, 2014 - Soc Nuclear Med
Absolute myocardial blood flow (MBF) and myocardial flow reserve (MFR) provide incremental
diagnostic and prognostic information over relative perfusion alone. Recent development …

Optimization of SPECT measurement of myocardial blood flow with corrections for attenuation, motion, and blood binding compared with PET

RG Wells, B Marvin, M Poirier, J Renaud… - Journal of Nuclear …, 2017 - Soc Nuclear Med
Myocardial blood flow (MBF) and myocardial flow reserve (MFR) measured with PET have
clinical value. SPECT cameras with solid-state detectors can obtain dynamic images for …

Test-Retest Precision of Myocardial Blood Flow Measurements With 99mTc-Tetrofosmin and Solid-State Detector Single Photon Emission Computed Tomography

…, I Radonjic, D Clackdoyle, J Do, B Marvin… - Circulation …, 2020 - Am Heart Assoc
Background: Measurement of myocardial blood flow (MBF) with single photon emission
computed tomography (SPECT) is feasible using cardiac cameras with solid-state detectors. …

Planar radionuclide angiography with a dedicated cardiac SPECT camera

RG Wells, B Marvin, G Kovalski, TD Ruddy - Journal of Nuclear Cardiology, 2013 - Elsevier
Background We compared a dedicated cardiac camera with a traditional system for left
ventricular (LV) functional measurements using gated blood-pool imaging. Methods 24-frame …

Measuring SPECT myocardial blood flow at the University of Ottawa Heart Institute

RG Wells, B Marvin - Journal of Nuclear Cardiology, 2021 - Springer
The introduction of new cardiac SPECT cameras has made it practical to do dynamic SPECT
imaging and opened the door to performing myocardial blood flow (MBF) imaging with …

Strategies for minimizing occupational radiation exposure in cardiac imaging

S Massalha, A Almufleh, G Small, B Marvin… - Current cardiology …, 2019 - Springer
Purpose of Review Radiation safety has been at the center of interest of both researchers
and healthcare institutions. This review will summarize and shed light on the various …

Reduced dose measurement of absolute myocardial blood flow using dynamic SPECT imaging in a porcine model

R Timmins, R Klein, J Petryk, B Marvin, L Wei… - Medical …, 2015 - Wiley Online Library
Purpose: Absolute myocardial blood flow (MBF) and myocardial flow reserve (MFR)
measurements provide important additional information over traditional relative perfusion imaging. …

Flow-dependent uptake of 123I-CMICE-013, a novel SPECT perfusion agent, compared with standard tracers

…, L Wei, J Petryk, Y Duan, B Marvin… - Journal of Nuclear …, 2015 - Soc Nuclear Med
Rotenone derivatives have shown promise in myocardial perfusion imaging (MPI). CMICE-013
is a novel 123 I-labeled rotenone derivative developed for SPECT MPI. The objective of …

Myocardial blood flow measured with a multi-pinhole SPECT camera: in vivo comparison to Rb-82 PET

RG Wells, B Marvin, M Poirier, R deKemp, R Klein… - 2016 - Soc Nuclear Med
284 Objectives Measurements of absolute myocardial blood flow (MBF) in the heart provide
incremental diagnostic and prognostic information over relative perfusion imaging alone. …

Patient motion on the GE Discovery CZT camera: Investigating the necessity of motion correction

A Kim, B Marvin, T Ruddy, RG Wells - 2010 - Soc Nuclear Med
2114 Objectives Patient motion of >=13mm (2 pixels) has been shown to cause artifacts that
may be misinterpreted as ischemia or scarring due to coronary artery disease. New …