A major obstacle to achieving long-term antiretroviral (ART) free remission or functional cure
of HIV infection is the presence of persistently infected cells that establish a long-lived viral …

Incorporation of d-amino acids into peptidoglycan is a unique metabolic feature of bacteria.
Since d-amino acids are not metabolic substrates in most mammalian tissues, this difference …

Most clinical trials exploring various combinations of chemo- and immunotherapy rely on
serial biopsy to provide information on immune response. The aim of this study was to assess …

Currently, there exists no accurate, noninvasive clinical imaging method to detect living
bacteria in vivo. Our goal is to provide a positron emission tomography (PET) method to image …

545 Introduction: Despite the striking success of antiretroviral therapy (ART) in HIV + patients,
HIV remains a serious global threat. HIV persists in anatomical reservoirs despite the use …

Currently, there exists no accurate, non-invasive clinical imaging method to detect living
bacteria in vivo. Our goal is to provide a positron emission tomography (PET) method to image …

540 Introduction: One of the challenges to the successful design and implementation of HIV
curative strategies is the limited ability to accurately quantify and characterize the whole-…

Positron emission tomography (PET) has emerged as a vital molecular imaging modality
providing metabolic insights that are essential for the diagnosis and treatment of disease. …

… Em 1985, Braile e cols. desenvolveram medidores específicos visando a mensuração do
perímetro da cúspide anterior, introduzindo um novo conceito para escolha do tamanho da …