The accumulation of lipid peroxides is recognized as a determinant of the occurrence of
ferroptosis. However, the sensors and amplifying process of lipid peroxidation linked to …

The function of mitophagy in cancer is controversial. ULK1 is critical for induction of
macroautophagy/autophagy and has a more specific role in mitophagy in response to hypoxia. Here, …

Most patients with triple negative breast cancer (TNBC) do not respond to anti-PD1/PDL1
immunotherapy, indicating the necessity to explore immune checkpoint targets. B7H3 is a …

Polycyclic aromatic hydrocarbons (PAHs) have been known for decades to threaten human
health. Various physical, chemical and biological methods have been developed to remove …

Due to its strong environmental robustness and high energy density, piezoelectric energy
harvesting is considered one of the most promising methods to power wireless sensor nodes …

Site-specific imaging agents play a key role in tumor targeting, but only a few agents are
currently available for inflammation targeting. Since the P2X7 receptor (P2X7R) is a promising …

c-MET-positive NSCLC is an important subtype accounting for about 5%~22% of lung cancer.
NSCLC patients with activating c-MET are intensively sensitive to c-MET selective receptor …

Ferroptosis, an iron-dependent lipid peroxidation-driven programmed cell death, is closely
related to cancer therapy. The development of druggable ferroptosis inducers and their …

Background Super-enhancers (SEs) play a crucial role in cancer, which is often associate
with activated oncogenes. However, little is known about how SEs facilitate tumour …

Objectives Programmed cell death-ligand 1 (PD-L1) is expressed on tumor cells (TC) and
tumor-infiltrating immune cells (IC). We conducted a retrospective study to investigate the …