Pulmonary squamous cell carcinoma is the second most common lung cancer subtype and
has a low 5-year survival rate at 17.6%. Complete resection with negative margins can be …

Purpose: Fluorescence-guided surgery using tumor-targeted contrast agents has been
developed to improve the completeness of oncologic resections. Quenched activity–based …

Suspicious nodules detected by radiography are often investigated by biopsy, but the
diagnostic yield of biopsies of small nodules is poor. Here we report a method—NIR-nCLE—to …

Importance Localization of subcentimeter ground glass opacities during minimally invasive
thoracoscopic lung cancer resections is a significant challenge in thoracic oncology. …

Intraoperative molecular imaging (IMI) has recently emerged as an important tool in the
armamentarium of surgical oncologists. IMI allows real-time assessment of oncologic resection …

Background The diagnostic yield of biopsies of solitary pulmonary nodules (SPNs) is low,
particularly in sub-solid lesions. We developed a method (NIR-nCLE) to achieve cellular level …

Bone marrow (BM) is a rich source of hematopoietic stem cells (HSCs), mesenchymal stem
cells (MSCs), and other important stem/progenitor cells. It is the traditional source of cells …

Background One of the novel advancements to enhance the visual aspects of lung cancer
identification is intraoperative molecular imaging (IMI), which can reliably detect tumors that …

Background. Early detection and complete resection are important prognostic factors for
esophageal cancer (EC). Intraoperative molecular imaging (IMI) using tumor-targeted tracers is …

Background Intraoperative molecular imaging has emerged as a potential tool in addressing
challenges faced during lung cancer surgery by localizing small lesions, ensuring negative …