Phosphatidylinositol 3-kinases (PI3Ks) and mammalian target of rapamycin (mTOR) play a
role in the pathogenesis of idiopathic pulmonary fibrosis (IPF). Omipalisib (GSK2126458) is a …

Purpose There is a lack of prognostic biomarkers in idiopathic pulmonary fibrosis (IPF) patients.
The objective of this study is to investigate the potential of 18 F-FDG-PET/ CT to predict …

Millions of people are affected by respiratory diseases, leading to a significant health burden
globally. Because of the current insufficient knowledge of the underlying mechanisms that …

Recently, there has been an increased interest in imaging different pulmonary disorders
using PET techniques. Previous work has shown, for static PET/CT, that air content in the lung …

Accurate PET quantitation requires a matched attenuation map. Obtaining matched CT
attenuation maps in the thorax is difficult due to the respiratory cycle which causes both motion …

PET with 18 F-FDG has been increasingly applied, predominantly in the research setting, to
study drug effects and pulmonary biology and to monitor disease progression and treatment …

PET/CT quantification of lung tissue is limited by several difficulties: the lung density and
local volume changes during respiration, the anatomical mismatch between PET and CT and …

The increase in cross-sectional imaging across medical disciplines has led to a rise in
incidentally-detected renal tumours worldwide [1]. Contemporary imaging cannot reliably …

Purpose Respiratory motion compensation in PET / CT and PET / MRI is essential as motion
is a source of image degradation (motion blur, attenuation artifacts). In previous work, we …

Background Matched attenuation maps are vital for obtaining accurate and reproducible
kinetic and static parameter estimates from PET data. With increased interest in PET/CT …