Histone deacetylases inhibitors as anti-angiogenic agents altering vascular endothelial growth factor signaling
…, S Blacher, E Verdin, JM Foidart, BV Nusgens… - Oncogene, 2002 - nature.com
Angiogenesis is a complex biological process involving the coordinated modulation of many
genes. Histone deacetylases (HDAC) are a growing family of enzymes that mediate the …
genes. Histone deacetylases (HDAC) are a growing family of enzymes that mediate the …
[PDF][PDF] Human Ehlers-Danlos syndrome type VII C and bovine dermatosparaxis are caused by mutations in the procollagen I N-proteinase gene
…, CM Lapière, DJ Prockop, BV Nusgens - The American Journal of …, 1999 - cell.com
Ehlers-Danlos syndrome (EDS) type VIIC is a recessively inherited connective-tissue
disorder, characterized by extreme skin fragility, characteristic facies, joint laxity, droopy skin, …
disorder, characterized by extreme skin fragility, characteristic facies, joint laxity, droopy skin, …
[HTML][HTML] Activated forms of MMP2 and MMP9 in abdominal aortic aneurysms
N Sakalihasan, P Delvenne, BV Nusgens… - Journal of vascular …, 1996 - Elsevier
… Nusgens PhD , Raymond Limet MD, PhD , Charles M. Lapière … C Bailly, S Dreze, D Asselineau,
B Nusgens, CM Lapière, M … Nusgens and Lapiere), CHU Sart Tilman, University of Liège. …
B Nusgens, CM Lapière, M … Nusgens and Lapiere), CHU Sart Tilman, University of Liège. …
[HTML][HTML] Topically applied vitamin C enhances the mRNA level of collagens I and III, their processing enzymes and tissue inhibitor of matrix metalloproteinase 1 in the …
BV Nusgens, AC Colige, CA Lambert… - Journal of Investigative …, 2001 - Elsevier
Ascorbic acid (vitamin C) is a cofactor required for the function of several hydroxylases and
monooxygenases. It is not synthesized in humans and some other animal species and has to …
monooxygenases. It is not synthesized in humans and some other animal species and has to …
In vitro tubulogenesis of endothelial cells by relaxation of the coupling extracellular matrix-cytoskeleton
…, CM Lapiere, BV Nusgens - Cardiovascular …, 2001 - academic.oup.com
Objective: This investigation aimed at determining the importance of the rigidity of the adhesive
support and the participation of the cytoskeleton in tubulogenesis of endothelial cells in …
support and the participation of the cytoskeleton in tubulogenesis of endothelial cells in …
Measurement of mechanical forces generated by skin fibroblasts embedded in a three-dimensional collagen gel
P Delvoye, P Wiliquet, JL Levêque, BV Nusgens… - Journal of Investigative …, 1991 - Elsevier
Mechanical activities developed by cells play a significant role in the embryogenesis,
development, and physiopathology of pluricellular organisms. A technique is described to measure …
development, and physiopathology of pluricellular organisms. A technique is described to measure …
[HTML][HTML] Cloning and characterization of ADAMTS-14, a novel ADAMTS displaying high homology with ADAMTS-2 and ADAMTS-3
…, SW Li, DJ Prockop, CM Lapiere, BV Nusgens - Journal of Biological …, 2002 - ASBMB
The processing of amino- and carboxyl-propeptides of fibrillar collagens is required to generate
collagen monomers that correctly assemble into fibrils. Mutations in the ADAMTS2gene, …
collagen monomers that correctly assemble into fibrils. Mutations in the ADAMTS2gene, …
cDNA cloning and expression of bovine procollagen I N-proteinase: a new member of the superfamily of zinc-metalloproteinases with binding sites for cells and other …
…, SW Li, AL Sieron, BV Nusgens… - Proceedings of the …, 1997 - National Acad Sciences
Procollagen N-proteinase (EC 3.4.24.14 ) cleaves the amino-propeptides in the processing
of type I and type II procollagens to collagens. Deficiencies of the enzyme cause …
of type I and type II procollagens to collagens. Deficiencies of the enzyme cause …
Modifications of the extracellular matrix of aneurysmal abdominal aortas as a function of their size
N Sakalihasan, A Heyeres, BV Nusgens… - European journal of …, 1993 - Elsevier
Collagen and elastin are the main extracellular matrix proteins providing the aortic wall with
adequate mechanical properties and resistance for proper function. Our study aimed at …
adequate mechanical properties and resistance for proper function. Our study aimed at …
Angiogenesis by fibroblast growth factor 4 is mediated through an autocrine up-regulation of vascular endothelial growth factor expression
…, A Hajitou, CM Calberg-Bacq, BV Nusgens… - Cancer research, 1997 - AACR
The infection of normal mouse mammary EF43 cells by a retroviral vector carrying either Fgf-3
(EF43.Fgf-3) or Fgf-4 (EF43.Fgf-4) cDNA resulted in the transformation of cells displaying …
(EF43.Fgf-3) or Fgf-4 (EF43.Fgf-4) cDNA resulted in the transformation of cells displaying …