It has been demonstrated in various murine tumor models that radiolabeled RGD-peptides
can be used for noninvasive determination of αvβ3 integrin expression. Introduction of sugar …

Overexpression of the translocator protein, TSPO (18 kDa), formerly known as the peripheral
benzodiazepine receptor, is a hallmark of activation of cells of monocytic lineage (microglia …

Focal cerebral ischemia leads to an inflammatory reaction involving an overexpression of
the peripheral benzodiazepine receptor (PBR)/18-kDa translocator protein (TSPO) in the …

Neuroinflammation is a process characterised by drastic changes in microglial morphology
and by marked upregulation of the 18-kDa translocator protein (TSPO) on the mitochondria. …

The data reported in this study show (1) that the proposed radiolabelling methods does not
modify the capcity of the antisense oligonucleotide to hybridize to its target complemetary …

We have designed new nanoprobes applicable for both positron emission tomography (PET)
and optical fluorescence in vivo imaging. Fluorine-18, which is commonly used for clinical …

Although brain neuroinflammation may play an instrumental role in the pathophysiology of
Alzheimer’s disease, its actual impact on disease progression remains controversial, being …

Introduction Increasing evidence suggests that neuroinflammation is active in Parkinson
disease (PD) and contributes to neurodegeneration. This process can be studied in vivo with …

FPyME (1-[3-(2-fluoropyridin-3-yloxy)propyl]pyrrole-2,5-dione) was designed as a [ 18 F]fluoropyridine-based
maleimide reagent for the prosthetic labeling of peptides and proteins via …

Purpose In this prospective study, our goal was to emphasize the diagnostic value of combining
11 C-choline and 18 F-FDG PET/CT for hepatocellular carcinoma (HCC) in patients with …