A quantitative analysis of the local connectivity between pyramidal neurons in layers 2/3 of the rat visual cortex
B Hellwig - Biological cybernetics, 2000 - Springer
This study provides a detailed quantitative estimate for local synaptic connectivity between
neocortical pyramidal neurons. A new way of obtaining such an estimate is presented. In …
neocortical pyramidal neurons. A new way of obtaining such an estimate is presented. In …
Testing for directed influences among neural signals using partial directed coherence
…, M Winterhalder, M Eichler, M Peifer, B Hellwig… - Journal of neuroscience …, 2006 - Elsevier
One major challenge in neuroscience is the identification of interrelations between signals
reflecting neural activity. When applying multivariate time series analysis techniques to neural …
reflecting neural activity. When applying multivariate time series analysis techniques to neural …
[18F]FDG-PET is superior to [123I]IBZM-SPECT for the differential diagnosis of parkinsonism
S Hellwig, F Amtage, A Kreft, R Buchert, OH Winz… - Neurology, 2012 - AAN Enterprises
Objective: Imaging of regional cerebral glucose metabolism with PET and striatal dopamine
D2/D3 receptors (D2R) with SPECT improves the differential diagnosis of parkinsonism. We …
D2/D3 receptors (D2R) with SPECT improves the differential diagnosis of parkinsonism. We …
Thalamic gray matter changes in unilateral Parkinsonian resting tremor: a voxel-based morphometric analysis of 3-dimensional magnetic resonance imaging
J Kassubek, FD Juengling, B Hellwig, J Spreer… - Neuroscience …, 2002 - Elsevier
The thalamus is assumed to be involved in the generation of Parkinsonian tremor. Ten patients
with tremor-dominant idiopathic Parkinson's disease (IPD) and strictly unilateral resting …
with tremor-dominant idiopathic Parkinson's disease (IPD) and strictly unilateral resting …
Single‐unit analysis of substantia nigra pars reticulata neurons in freely behaving rats with genetic absence epilepsy
C Deransart, B Hellwig, M Heupel‐Reuter, JF Léger… - …, 2003 - Wiley Online Library
Purpose: The substantia nigra pars reticulata (SNpr) is assumed to be involved in the control
of several kinds of epileptic seizures, an assumption based mostly on neuropharmacologic …
of several kinds of epileptic seizures, an assumption based mostly on neuropharmacologic …
Deep brain stimulation of the nucleus ventralis intermedius for Holmes (rubral) tremor and associated dystonia caused by upper brainstem lesions: report of two cases
G Nikkhah, T Prokop, B Hellwig, CH Lücking… - Neurosurgical …, 2004 - thejns.org
✓Holmes tremor is caused by structural lesions in the perirubral area of the midbrain. Patients
often present with associated symptoms such as dystonia and paresis, which are usually …
often present with associated symptoms such as dystonia and paresis, which are usually …
Tremor-correlated neuronal activity in the subthalamic nucleus of Parkinsonian patients
Tremor in Parkinson's disease (PD) is generated by an oscillatory neuronal network consisting
of cortex, basal ganglia and thalamus. The subthalamic nucleus (STN) which is part of the …
of cortex, basal ganglia and thalamus. The subthalamic nucleus (STN) which is part of the …
Direct or indirect? Graphical models for neural oscillators
B Schelter, M Winterhalder, B Hellwig… - Journal of Physiology …, 2006 - Elsevier
Univariate and bivariate time series analysis techniques have enabled new insights into
neural processes. However, these techniques are not feasible to distinguish direct and indirect …
neural processes. However, these techniques are not feasible to distinguish direct and indirect …
Synapses on axon collaterals of pyramidal cells are spaced at random intervals: a Golgi study in the mouse cerebral cortex
B Hellwig, A Schüz, A Aertsen - Biological cybernetics, 1994 - Springer
In this study we investigated the arrangement of synapses on local axon collaterals of Golgi-stained
pyramidal neurons in the mouse cerebral cortex. As synaptic markers we considered …
pyramidal neurons in the mouse cerebral cortex. As synaptic markers we considered …
Time-variant estimation of directed influences during Parkinsonian tremor
…, J Wohlmuth, M Jachan, F Amtage, B Hellwig… - Journal of Physiology …, 2009 - Elsevier
The inference of interaction structures in multidimensional time series is a major challenge
not only in neuroscience but in many fields of research. To gather information about the …
not only in neuroscience but in many fields of research. To gather information about the …