This study provides a detailed quantitative estimate for local synaptic connectivity between
neocortical pyramidal neurons. A new way of obtaining such an estimate is presented. In …

One major challenge in neuroscience is the identification of interrelations between signals
reflecting neural activity. When applying multivariate time series analysis techniques to neural …

Objective: Imaging of regional cerebral glucose metabolism with PET and striatal dopamine
D2/D3 receptors (D2R) with SPECT improves the differential diagnosis of parkinsonism. We …

The thalamus is assumed to be involved in the generation of Parkinsonian tremor. Ten patients
with tremor-dominant idiopathic Parkinson's disease (IPD) and strictly unilateral resting …

Purpose: The substantia nigra pars reticulata (SNpr) is assumed to be involved in the control
of several kinds of epileptic seizures, an assumption based mostly on neuropharmacologic …

✓Holmes tremor is caused by structural lesions in the perirubral area of the midbrain. Patients
often present with associated symptoms such as dystonia and paresis, which are usually …

Tremor in Parkinson's disease (PD) is generated by an oscillatory neuronal network consisting
of cortex, basal ganglia and thalamus. The subthalamic nucleus (STN) which is part of the …

Univariate and bivariate time series analysis techniques have enabled new insights into
neural processes. However, these techniques are not feasible to distinguish direct and indirect …

In this study we investigated the arrangement of synapses on local axon collaterals of Golgi-stained
pyramidal neurons in the mouse cerebral cortex. As synaptic markers we considered …

The inference of interaction structures in multidimensional time series is a major challenge
not only in neuroscience but in many fields of research. To gather information about the …