Purpose The purpose of the present study is to evaluate safety, human radiation dosimetry,
and optimal imaging time of [ 89 Zr]trastuzumab in patients with HER2-positive breast cancer. …

Since its discovery, the human epidermal growth factor 2 (HER2) has been extensively studied.
Presently, there are 2 standard diagnostic techniques to assess HER2 status in biopsies: …

Purpose To evaluate whether tumor uptake of [ 89 Zr]trastuzumab can distinguish HER2-positive
from HER2-negative breast cancer. Methods Women with HER2-positive (n = 34) and …

Background Amivantamab is a novel bispecific antibody that simultaneously targets the
epidermal growth factor receptor (EGFR) and the hepatocyte growth factor receptor (HGFR/c-…

Breast cancer is the most common cancer in women worldwide. The heterogeneity of breast
cancer and drug resistance to therapies make the diagnosis and treatment difficult. …

The morbidity associated with pediatric medulloblastoma, in particular in patients who
develop leptomeningeal metastases, remains high in the absence of effective therapies. …

Background: The success of human epidermal growth factor receptor 2 (HER2)-targeted
therapy depends on accurate characterization of HER2 expression, but current methods …

Radioimmunotherapies with monoclonal antibodies to the B-lymphocyte antigen 20 (CD20)
are effective treatments for B-cell lymphomas, but US Food and Drug Administration–…

The successful development and translation of PET imaging agents targeting β-amyloid
plaques and hyperphosphorylated tau tangles have allowed for in vivo detection of these …

Simple Summary Breast cancer is currently the most common type of diagnosed cancer
worldwide. Noninvasive imaging of therapeutic targets or biomarkers for breast cancer has the …