A vaccine targeting mutant IDH1 induces antitumour immunity
Monoallelic point mutations of isocitrate dehydrogenase type 1 (IDH1) are an early and defining
event in the development of a subgroup of gliomas 1 , 2 , 3 and other types of tumour 4 , …
event in the development of a subgroup of gliomas 1 , 2 , 3 and other types of tumour 4 , …
[HTML][HTML] Hotspot mutations in H3F3A and IDH1 define distinct epigenetic and biological subgroups of glioblastoma
…, CM Kramm, J Felsberg, C Hartmann, B Wiestler… - Cancer cell, 2012 - cell.com
Glioblastoma (GBM) is a brain tumor that carries a dismal prognosis and displays considerable
heterogeneity. We have recently identified recurrent H3F3A mutations affecting two …
heterogeneity. We have recently identified recurrent H3F3A mutations affecting two …
Autoencoders for unsupervised anomaly segmentation in brain MR images: a comparative study
Deep unsupervised representation learning has recently led to new approaches in the field
of Unsupervised Anomaly Detection (UAD) in brain MRI. The main principle behind these …
of Unsupervised Anomaly Detection (UAD) in brain MRI. The main principle behind these …
Identifying the best machine learning algorithms for brain tumor segmentation, progression assessment, and overall survival prediction in the BRATS challenge
…, R Wiest, J Kirschke, B Wiestler… - arXiv preprint arXiv …, 2018 - arxiv.org
Gliomas are the most common primary brain malignancies, with different degrees of
aggressiveness, variable prognosis and various heterogeneous histologic sub-regions, ie, …
aggressiveness, variable prognosis and various heterogeneous histologic sub-regions, ie, …
ATRX and IDH1-R132H immunohistochemistry with subsequent copy number analysis and IDH sequencing as a basis for an “integrated” diagnostic approach for …
Diffuse gliomas are represented in the 2007 WHO classification as astrocytomas,
oligoastrocytomas and oligodendrogliomas of grades II and III and glioblastomas WHO grade IV. …
oligoastrocytomas and oligodendrogliomas of grades II and III and glioblastomas WHO grade IV. …
Prognostic or predictive value of MGMT promoter methylation in gliomas depends on IDH1 mutation
…, B Hentschel, M Platten, A Schilling, B Wiestler… - Neurology, 2013 - AAN Enterprises
Objective: To explore whether the isocitrate dehydrogenase 1 (IDH1) or 1p/19q status
determines the prognostic vs predictive role of O 6 -methylguanine-DNA methyltransferase (MGMT…
determines the prognostic vs predictive role of O 6 -methylguanine-DNA methyltransferase (MGMT…
Brain tumour cells interconnect to a functional and resistant network
…, J Blaes, S Weil, H Horstmann, B Wiestler… - Nature, 2015 - nature.com
Astrocytic brain tumours, including glioblastomas, are incurable neoplasms characterized
by diffusely infiltrative growth. Here we show that many tumour cells in astrocytomas extend …
by diffusely infiltrative growth. Here we show that many tumour cells in astrocytomas extend …
[HTML][HTML] The liver tumor segmentation benchmark (lits)
In this work, we report the set-up and results of the Liver Tumor Segmentation Benchmark (LiTS),
which was organized in conjunction with the IEEE International Symposium on …
which was organized in conjunction with the IEEE International Symposium on …
The rsna-asnr-miccai brats 2021 benchmark on brain tumor segmentation and radiogenomic classification
The BraTS 2021 challenge celebrates its 10th anniversary and is jointly organized by the
Radiological Society of North America (RSNA), the American Society of Neuroradiology (ASNR…
Radiological Society of North America (RSNA), the American Society of Neuroradiology (ASNR…
Radiomics in radiooncology–challenging the medical physicist
Purpose Noticing the fast growing translation of artificial intelligence (AI) technologies to
medical image analysis this paper emphasizes the future role of the medical physicist in this …
medical image analysis this paper emphasizes the future role of the medical physicist in this …