OBJECTIVE Camptocormia is a potentially debilitating condition in the progression of
Parkinson’s disease (PD). It is described as an abnormal forward flexion while standing that …

The increasing number of studies demonstrates the high potency of the intrathecal (IT) route
for the delivery of biopharmaceuticals to the central nervous system (CNS). Our earlier data …

Purpose Primary spinal cord tumors are rare, and evidence-based management of these
patients remains a source of controversy. This study used a large cohort of low-grade spinal …

Large blood vessels entering the CNS are surrounded by perivascular spaces that communicate
with the cerebrospinal fluid and, at their termini, with the interstitial space. Solutes and …

Background Posterior fossa craniotomies can be complicated by cerebrospinal fluid (CSF)
leaks, infection, meningitis, neurologic deficits, and intracranial hypotension caused by …

Background Venous malformations (VMs) are slow flowing congenital vascular malformations
that demonstrate continuous growth. They are prone to bleeding and frequent invasion of …

Neuronuclear imaging has been used for several decades in the study of primary neurodegenerative
conditions, such as dementia and parkinsonian syndromes, both for research and …

Alcohol intoxication is a common risk factor of traumatic brain injury (TBI) and carries a
significant health-care burden on underserved patients. Patients with chronic alcohol use may …

Transplant surgery is a predominantly male specialty with high burnout rates. There are
currently limited data regarding how programs can attract a diverse applicant pool to the field of …

192 Objectives Test strategies for integrating use of amyloid imaging and FDG PET information
to predict rates of cognitive and functional decline. Methods Baseline florbetapir and FDG …