Background & Aims Autoimmune hepatitis (AIH) is an uncommon autoimmune liver disease
of unknown etiology. We used a genome-wide approach to identify genetic variants that …

Estimates of people suffering from overweight (one billion) and obesity (300 million) are
increasing. The accumulation of triglycerides in the liver, in the absence of excess alcohol intake…

BACKGROUND & AIMS: Current treatment strategies in autoimmune hepatitis (AIH) include
long-term treatment with corticosteroids and/or azathioprine. Here we determined the risk of …

Background and aims. Epidemiological data on autoimmune hepatitis (AIH) are scarce. In this
study, we determined the clinical and epidemiological characteristics of AIH patients in the …

A major part of morbidity and mortality after liver resections is caused by inadequate remnant
liver function leading to liver failure. It is therefore important to develop accurate diagnostic …

The classical human leukocyte antigen (HLA)-DRB1* 03: 01 and HLA-DRB1* 04: 01 alleles
are established autoimmune hepatitis (AIH) risk alleles. To study the immune-modifying …

… the data, Martine Baven and Bart van Hoek wrote the paper, Bart van Hoek designed the
research, and Aad van den Berg, Henk van Buuren, Bart Verwer, Karin van Nieuwkerk and …

Objective Type 2 diabetes mellitus is a metabolic disorder characterized by insulin
resistance. Previous studies in patients demonstrated that plasma levels of cathepsin D (CTSD), …

Background Azathioprine ( AZA ) and mercaptopurine ( MP ) are the cornerstone of steroid‐sparing
strategies in autoimmune hepatitis ( AIH ). Up to 20% of patients do not tolerate or …

NAFLD is closely related with the metabolic syndrome (MetS) and increased risk of
cardiovascular disease. Liver fat associates with post‐prandial hypertriglyceridemia, potentially …