Molecular imaging of inflammation and fibrosis in pressure overload heart failure

A Glasenapp, K Derlin, M Gutberlet, A Hess… - Circulation …, 2021 - Am Heart Assoc
Rationale: Tissue inflammation and subsequent fibrosis contribute to ventricle remodelling
after ischemic injury and have emerged as viable therapeutic targets. Comparatively, little is …

Multimodality imaging of inflammation and ventricular remodeling in pressure-overload heart failure

A Glasenapp, K Derlin, Y Wang… - Journal of Nuclear …, 2020 - Soc Nuclear Med
Inflammation contributes to ventricular remodeling after myocardial ischemia, but its role in
nonischemic heart failure is poorly understood. Local tissue inflammation is difficult to assess …

[HTML][HTML] Anesthesia and analgesia for experimental craniotomy in mice and rats: a systematic scoping review comparing the years 2009 and 2019

…, A Bleich, V Buchecker, A Glasenapp… - Frontiers in …, 2023 - frontiersin.org
Experimental craniotomies are a common surgical procedure in neuroscience. Because
inadequate analgesia appears to be a problem in animal-based research, we conducted this …

Subcutaneous and orally self-administered high-dose carprofen in male and female mice: pharmacokinetics, tolerability and impact on cage-side pain indicators

A Glasenapp, JP Bankstahl, H Baehre, S Glage… - bioRxiv, 2023 - biorxiv.org
Surgical interventions in mice are prerequisite in various research fields and require
appropriate pain relief, not only to ensure animal welfare but also to avoid influence of pain on …

Multimodality imaging of cardio-renal inflammation crosstalk after acute cardiac injury in mice

M Strunk, A Hess, A Glasenapp, F Bengel, J Thackeray… - 2023 - Soc Nuclear Med
P562 Introduction: Cardiovascular disease and heart failure are associated with impaired
renal function, but the biologic mechanisms underlying this interorgan crosstalk remain poorly …

[PDF][PDF] Multimodality Molecular Imaging of Inflammation and Fibrosis in Pressure Overload-Induced Heart Failure and After Mechanical Ventricular Unloading

A Glasenapp - 2020 - elib.tiho-hannover.de
… of subsequent heart failure progression” Aylina Glasenapp, Katja Derlin, Marcel Gutberlet, …
of cardiac remodeling following ventricular unloading” Aylina Glasenapp, Katja Derlin, Marcel …

Imaging non-coding microRNA upregulation in pressure overload heart failure using the complementary anti-miR-21 locked nucleic acid

J Thackeray, E Janssen, A Glasenapp, J Fiedler… - 2021 - Soc Nuclear Med
138 Objectives: Non-coding ribonucleic acids (RNA) are upregulated in heart failure, during
which they modulate ventricle remodeling. Selective inhibitors of microRNA-21 (miR-21) …

Multimodal imaging identifies cardiac chemokine receptor CXCR4 upregulation in response to pressure overload as a predictor of subsequent heart failure …

A Glasenapp, K Derlin, M Gutberlet, BLN Langer… - 2019 - Soc Nuclear Med
34 Purpose: Excessive inflammation after myocardial infarction is a critical contributor to
ventricular remodeling, and a potential therapeutic target. The role in non-ischemic heart failure …

Optimization of Artificial Siderophores as 68Ga-Complexed PET Tracers for In Vivo Imaging of Bacterial Infections

C Peukert, LNB Langer, SM Wegener… - Journal of Medicinal …, 2021 - ACS Publications
The diagnosis of bacterial infections at deep body sites benefits from noninvasive imaging
of molecular probes that can be traced by positron emission tomography (PET). We …

[CITATION][C] Meet the First Authors

MTD NaV - Circulation Research, 2021