PET/CT with 18 F-FDG is an important noninvasive diagnostic tool for management of patients
with lymphoma, and its use may surpass current guideline recommendations. The aim of …

Background Inherited bone marrow failure syndromes are rare genetic disorders characterized
by bone marrow failure, congenital anomalies, and cancer predisposition. Available …

Fanconi anemia (FA), an inherited bone marrow failure (BMF) syndrome, caused by mutations
in DNA repair genes, is characterized by congenital anomalies, aplastic anemia, high risk …

Background Most patients with anemia are diagnosed through clinical phenotype and basic
laboratory testing. Nonetheless, in cases of rare congenital anemias, some patients remain …

Purpose Fluoro-deoxyglucose positron emmission tomography combined with computed
tomography (FDG-PET/CT) is superior to iliac bone marrow biopsy (iBMB) for detection of bone …

Although the role of MYCN amplification in neuroblastoma is well established, the biological
and clinical characteristics of the 2p gain region harboring the MYCN gene remain unclear. …

Background The relative frequency of mutated genes among patients with severe congenital
neutropenia (SCN) may differ between various ethnic groups. To date, few population‐…

Heparanase is an endoglycosidase that specifically cleaves heparan sulfate (HS) side
chains of heparan sulfate proteoglycans, the major proteoglycan in the extracellular matrix (ECM) …

In order to understand the primary defect in this family we performed several more studies.
Class-switch recombination was evaluated by measuring IgE production. Peripheral blood …

Purpose 18 F-fluorodeoxyglucose ( 18 F-FDG) positron emission tomography (PET) imaging
has been used in the assessment of paediatric malignancies. PET/CT increases the …