User profiles for Axel Rominger

Axel Rominger

Professor für Nuklearmedizin
Verified email at insel.ch
Cited by 9883

Real versus imagined locomotion: a [18F]-FDG PET-fMRI comparison

C La Fougere, A Zwergal, A Rominger, S Förster… - Neuroimage, 2010 - Elsevier
The cortical, cerebellar and brainstem BOLD-signal changes have been identified with fMRI
in humans during mental imagery of walking. In this study the whole brain activation and …

sTREM 2 cerebrospinal fluid levels are a potential biomarker for microglia activity in early‐stage Alzheimer's disease and associate with neuronal injury markers

…, M Brendel, A Rominger… - EMBO molecular …, 2016 - embopress.org
TREM 2 is an innate immune receptor expressed on the surface of microglia. Loss‐of‐function
mutations of TREM 2 are associated with increased risk of Alzheimer's disease ( AD ). …

Loss of TREM2 function increases amyloid seeding but reduces plaque-associated ApoE

…, P Bartenstein, D Edbauer, A Rominger… - Nature …, 2019 - nature.com
Coding variants in the triggering receptor expressed on myeloid cells 2 (TREM2) are associated
with late-onset Alzheimer’s disease (AD). We demonstrate that amyloid plaque seeding …

18F-FDG PET/CT identifies patients at risk for future vascular events in an otherwise asymptomatic cohort with neoplastic disease

A Rominger, T Saam, S Wolpers… - Journal of Nuclear …, 2009 - Soc Nuclear Med
Our objective was to evaluate the association of arterial 18 F-FDG uptake and calcifications
in large arteries as detected by 18 F-FDG PET/CT with the subsequent occurrence of …

Microglial activation states drive glucose uptake and FDG-PET alterations in neurodegenerative diseases

…, N Franzmeier, K Baumann, A Rominger… - Science translational …, 2021 - science.org
2-Deoxy-2-[ 18 F]fluoro-d-glucose positron emission tomography (FDG-PET) is widely used
to study cerebral glucose metabolism. Here, we investigated whether the FDG-PET signal is …

Performance characteristics of the biograph vision quadra PET/CT system with a long axial field of view using the NEMA NU 2-2018 standard

…, A Afshar-Oromieh, K Shi, A Rominger… - Journal of nuclear …, 2022 - Soc Nuclear Med
Our purpose was to evaluate the performance of the Biograph Vision Quadra PET/CT
system. This new system is based on the Biograph Vision 600, using the same silicon …

[HTML][HTML] Clinical performance of long axial field of view PET/CT: a head-to-head intra-individual comparison of the Biograph Vision Quadra with the Biograph Vision …

…, K Shi, A Afshar-Oromieh, A Rominger - European journal of …, 2021 - Springer
Purpose To investigate the performance of the new long axial field-of-view (LAFOV) Biograph
Vision Quadra PET/CT and a standard axial field-of-view (SAFOV) Biograph Vision 600 …

[HTML][HTML] Large language models (LLM) and ChatGPT: what will the impact on nuclear medicine be?

…, T Pyka, G Prenosil, K Shi, A Rominger… - European journal of …, 2023 - Springer
There has been substantial press recently regarding the impressive performance of large
language models (LLM), particularly the OpenAI tool “Chat Generative Pre-Trained Transformer…

Intravenous immunoglobulin for treatment of mild-to-moderate Alzheimer's disease: a phase 2, randomised, double-blind, placebo-controlled, dose-finding trial

R Dodel, A Rominger, P Bartenstein, F Barkhof… - The Lancet …, 2013 - thelancet.com
Background Three small trials suggest that intravenous immunoglobulin can affect biomarkers
and symptoms of mild-to-moderate Alzheimer's disease. We tested the safety, effective …

[HTML][HTML] Preliminary experience with dosimetry, response and patient reported outcome after 177Lu-PSMA-617 therapy for metastatic castration-resistant prostate …

…, P Bartenstein, C Gratzke, S Lehner, A Rominger - Oncotarget, 2017 - ncbi.nlm.nih.gov
Prostate cancer can be targeted by ligands to the prostate-specific membrane antigen (PSMA).
We aimed to evaluate dosimetry, safety and efficacy of 177 Lu-PSMA-617 radioligand …