Fully Automated Radiosynthesis of [11C]Guanidines for Cardiac PET Imaging

AY Zhao, AF Brooks, DM Raffel, J Stauff… - ACS Medicinal …, 2020 - ACS Publications
Radiolabeled guanidines such as meta-iodobenzylguanidine (MIBG) find utility in nuclear
medicine as both diagnostic imaging agents and radiotherapeutics and, over the years, …

Evaluation of enzyme substrate radiotracers as PET/MRS hybrid imaging agents

AF Brooks, LR Drake, X Shao, A Zhao… - ACS Medicinal …, 2018 - ACS Publications
The development of a positron emission tomography (PET)/magnetic resonance spectroscopy
(MRS) hybrid imaging agent allows for functional imaging by both methods with a single …

Fully Automated Radiosynthesis of Symmetric and Asymmetric [11C] Guanidines

K Mhanna, X Shao, A Zhao, A Brooks, D Raffel, P Scott - 2021 - Soc Nuclear Med
1455 Introduction: Guanidines are present in a variety of naturally occurring products and is
a key feature of the imaging agent and radiotherapeutic Iobenguane (MIBG) 1 . Recently, a …

Fully Automated Radiosynthesis of [11C] Guanidines and Bioevaluation of [11C] PHPOG as Cardiac Imaging Agent

A Zhao, A Brooks, D Raffel, P Scott, X Shao - 2020 - Soc Nuclear Med
63 Introduction: Guanidine has been found in a variety of natural products 1 and many
guanidine synthesis methods have been investigated. However, radiosyntheses of guanidines …

Synthesis and Evaluation of 4-(2-fluoro-4-nitrophenoxy)-1-([11C] methyl)-1, 2, 3, 6-tetrahydropyridine as a MAO-A Selective PET-MRI Hybrid Imaging Probe

A Brooks, X Shao, L Drake, A Zhao, P Scott, M Kilbourn - 2016 - Soc Nuclear Med
1219 Objectives As a potential hybrid PET-MRI imaging agent for monoamine oxidase-A (MAO-A)
we combined our concept of carbon-11 labeled 1-methyl-4-aryloxy-1,2,3,6-…

Enzyme Substrate Trapped Metabolite Radiotracers Evaluated for the Development of PET/MR Hybrid Imaging Agents

A Brooks, X Shao, L Drake, A Zhao, P Scott, M Kilbourn - 2017 - Soc Nuclear Med
268 Objectives: MR imaging agents require high concentrations, which eliminates the
possibility of using radioligands to develop a PET/MR hybrid imaging agent. Enzyme substrates …

High value information in engineering organisations

Y Zhao, LCM Tang, MJ Darlington, SA Austin… - International Journal of …, 2008 - Elsevier
The management of information in engineering organisations is facing a particular challenge
in the ever-increasing volume of information. It has been recognised that an effective …

HPV test results stratify risk for histopathologic follow-up findings of high-grade cervical intra-epithelial neoplasia in women with low-grade squamous intra-epithelial …

A Heider, RM Austin, C Zhao - Acta cytologica, 2011 - karger.com
Objective: Age-adjusted evaluations have explored the possible utility of human papillomavirus
(HPV) test results in women with low-grade squamous intra-epithelial lesion (LSIL) Paps. …

Characterizing the 3-D urban morphology transformation to understand urban-form dynamics: A case study of Austin, Texas, USA

C Zhao, Q Weng, AM Hersperger - Landscape and urban planning, 2020 - Elsevier
… Thus, this study focuses on the Austin metropolitan area in … In line with the Austin’s urban
policies and planning over the … assess the conformance of the process with Austin’s goals, we …

What role should cytology play in cervical cancer screening?

RB Perkins, RM Austin, C Zhao, D Saslow… - Journal of Lower …, 2019 - journals.lww.com
Austin and Zhao argue that cotesting must be presumed superior until prospective trials of
Austin and Zhao also argue that HPV screening overdiagnoses lesions destined to regress …