[HTML][HTML] Stable tumor vessel normalization with pO2 increase and endothelial PTEN activation by inositol trispyrophosphate brings novel tumor treatment
…, J Kotlinowski, KC Fylaktakidou, A Vidal… - Journal of molecular …, 2013 - Springer
Tumor hypoxia is a characteristic of cancer cell growth and invasion, promoting angiogenesis,
which facilitates metastasis. Oxygen delivery remains impaired because tumor vessels …
which facilitates metastasis. Oxygen delivery remains impaired because tumor vessels …
[HTML][HTML] Focus on the Controversial Aspects of 64Cu-ATSM in Tumoral Hypoxia Mapping by PET Imaging
M Colombié, S Gouard, M Frindel, A Vidal… - Frontiers in …, 2015 - frontiersin.org
Mapping tumor hypoxia is a great challenge in positron emission tomography (PET)
imaging as the precise functional information of the biological processes is needed for many …
imaging as the precise functional information of the biological processes is needed for many …
[HTML][HTML] Potential for nuclear medicine therapy for glioblastoma treatment
C Bailly, A Vidal, C Bonnemaire… - Frontiers in …, 2019 - frontiersin.org
Glioblastoma is the most common malignant adult brain tumor and has a very poor patient
prognosis. The mean survival for highly proliferative glioblastoma is only 10 to 14 months …
prognosis. The mean survival for highly proliferative glioblastoma is only 10 to 14 months …
[HTML][HTML] 64Cu-ATSM/64Cu-Cl2 and their relationship to hypoxia in glioblastoma: a preclinical study
…, D Divoux, M Ibazizène, S Guillouet, L Barré, A Vidal… - EJNMMI research, 2019 - Springer
Background Diacetyl-bis(N4-methylthiosemicarbazone), labeled with 64Cu ( 64 Cu-ATSM)
has been suggested as a promising tracer for imaging hypoxia. However, various …
has been suggested as a promising tracer for imaging hypoxia. However, various …
Small rigid platforms functionalization with quaternary ammonium: targeting extracellular matrix of chondrosarcoma
E Miot-Noirault, A Vidal, J Morlieras, P Bonazza… - … , Biology and Medicine, 2014 - Elsevier
This work takes place in the “cartilage targeting strategy”, consisting in using the quaternary
ammonium (QA) function as a vector to proteoglycans (PGs) of extracellular matrix (ECM). …
ammonium (QA) function as a vector to proteoglycans (PGs) of extracellular matrix (ECM). …
[HTML][HTML] Is there an interest to use deuteron beams to produce non-conventional radionuclides?
…, N Michel, M Mokili, M Pageau, A Vidal - Frontiers in …, 2015 - frontiersin.org
With the recent interest on the theranostic approach, there has been a renewed interest for
alternative radionuclides in nuclear medicine. They can be produced using common …
alternative radionuclides in nuclear medicine. They can be produced using common …
Single photon emission computed tomography/positron emission tomography imaging and targeted radionuclide therapy of melanoma: new multimodal fluorinated …
…, J Papon, R Boisgard, M Bayle, A Vidal… - Journal of medicinal …, 2011 - ACS Publications
This study reports a series of 14 new iodinated and fluorinated compounds offering both
early imaging ( 123 I, 124 I, 18 F) and systemic treatment ( 131 I) of melanoma potentialities. …
early imaging ( 123 I, 124 I, 18 F) and systemic treatment ( 131 I) of melanoma potentialities. …
Synthesis, Radiofluorination, and in Vivo Evaluation of Novel Fluorinated and Iodinated Radiotracers for PET Imaging and Targeted Radionuclide Therapy of …
EMF Billaud, L Rbah-Vidal, A Vidal… - Journal of medicinal …, 2013 - ACS Publications
Our project deals with a multimodal approach using a single fluorinated and iodinated
melanin-targeting structure and offering both imaging (positron emission tomography (PET)/…
melanin-targeting structure and offering both imaging (positron emission tomography (PET)/…
Early detection and longitudinal monitoring of experimental primary and disseminated melanoma using [18F]ICF01006, a highly promising melanoma PET tracer
L Rbah-Vidal, A Vidal, S Besse, F Cachin… - European journal of …, 2012 - Springer
Purpose Here, we report a new and rapid radiosynthesis of 18 F-N-[2-(diethylamino)ethyl]-6-fluoro-pyridine-3-carboxamide
([ 18 F]ICF01006), a molecule with a high specificity for …
([ 18 F]ICF01006), a molecule with a high specificity for …
[HTML][HTML] Theranostic approach for metastatic pigmented melanoma using ICF15002, a multimodal radiotracer for both PET imaging and targeted radionuclide therapy
L Rbah-Vidal, A Vidal, EMF Billaud, S Besse… - Neoplasia, 2017 - Elsevier
PURPOSE: This work reports, in melanoma models, the theranostic potential of ICF15002 as
a single fluorinated and iodinated melanin-targeting compound. METHODS: Studies were …
a single fluorinated and iodinated melanin-targeting compound. METHODS: Studies were …