[HTML][HTML] Mutations in the iodotyrosine deiodinase gene and hypothyroidism

JC Moreno, W Klootwijk, H van Toor… - … England Journal of …, 2008 - Mass Medical Soc
DEHAL1 has been identified as the gene encoding iodotyrosine deiodinase in the thyroid,
where it controls the reuse of iodide for thyroid hormone synthesis. We screened patients with …

Iodine‐induced thyrotoxicosis: analysis of eighty‐five consecutive cases

AF LEGER, JP MASSIN, MF LAURENT… - European journal of …, 1984 - Wiley Online Library
Iodine‐induced thyrotoxicosis was documented in eighty‐five cases. Eighty per cent occur
in apparently normal thyroid glands; 60% among them occur in males. Amiodarone …

Decreased uptake of therapeutic doses of iodine-131 after 185-MBq iodine-131 diagnostic imaging for thyroid remnants in differentiated thyroid carcinoma

FA Leger, M Izembart, F Dagousset, L Barritault… - European journal of …, 1998 - Springer
We performed a prospective random study to assess possible thyroid stunning by a 185-MBq
iodine-131 dose used to diagnose thyroid remnants. Patients with differentiated thyroid …

[99mTc]‐Sestamibi parathyroid scintigraphy in chronic haemodialysis patients: static and dynamic explorations

…, C Heuguerot, L Fajardo, A Léger… - Nephrology Dialysis …, 2000 - academic.oup.com
Background. The place of parathyroid gland imaging by [ 99m Tc](technetium)‐sestamibi
scintigraphy in uraemic patients with secondary hyperparathyroidism remains a matter of …

Radioiodine therapy of the autonomous thyroid nodule in patients with or without visible extranodular activity.

…, A Alcais, A Chevalier, AF Léger… - Journal of Nuclear …, 1995 - europepmc.org
Methods We retrospectively reviewed the records of 88 patients who received 131I (intended
dose of 80 Gy) for an ATN, of whom 39 had evidence of extranodular activity (ENA) and 76 …

Immunological studies of autoimmune thyroid disorders: abnormalities in the inducer T cell subset and proliferative responses to autologous and allogeneic …

C Fournier, H Chen, A Leger… - Clinical and experimental …, 1983 - ncbi.nlm.nih.gov
Various immunological parameters were investigated in patients with Hashimoto's thyroiditis
(HT) and Graves' disease (GD). The total T cell numbers were significantly decreased in …

[PDF][PDF] Re: Thyroid Iodine Content Measured by X-Ray Fluorescence in Amiodarone-Induced Thyrotoxicosis: Concise Communication—Reply

A Leger, P Fragu - Journal of Nuclear Medicine, 1984 - Soc Nuclear Med
In Graves' disease, the thyroid iodine content was normal in 58% ofour cases, high in 20%,
and low in only 22%, which is at variance with Jonckheer's data (3). However, we agree that …

Radioiodine Scanning of the Thyroid Searching for the Other Lobe

…, M IZEMBART, B BEROLATTI, A LÉGER… - Clinical nuclear …, 1993 - journals.lww.com
Nuclear images (I-123 or l-131) of a single thyroid lobe From the Department of Nuclear
Medicine and Biophysics, are often encountered in the exploration of thyroid dis-Hôpital Necker …

Proportion of various types of thyroid disorders among newborns with congenital hypothyroidism and normally located gland: a regional cohort study

…, C Garel, P Czernichow, J Léger - Clinical …, 2005 - Wiley Online Library
Objective To determine the proportion of the various types of thyroid disorders among
newborns detected by the neonatal TSH screening programme, with a normally located thyroid …

Outpatient thyroid remnant ablation using repeated low 131-iodine activities (740 MBq/20 mCi× 2) in patients with low-risk differentiated thyroid cancer

…, L Groussin, RJ Marlowe, FA Leger… - The Journal of …, 2012 - academic.oup.com
Context: In low-risk differentiated thyroid cancer (DTC), postoperative 131 I remnant ablation
should employ a minimum effective activity; reports increasingly suggest efficacy of low …