Clinical significance and therapeutic potential of the programmed death-1 ligand/programmed death-1 pathway in human pancreatic cancer

T Nomi, M Sho, T Akahori, K Hamada, A Kubo… - Clinical cancer …, 2007 - AACR
Purpose: The programmed death-1 ligand/programmed death-1 (PD-L/PD-1) pathway has
been recently suggested to play a pivotal role in the immune evasion of tumors from host …

Development of definitive endoderm from embryonic stem cells in culture

A Kubo, K Shinozaki, JM Shannon, V Kouskoff… - 2004 - journals.biologists.com
The cellular and molecular events regulating the induction and tissue-specific differentiation
of endoderm are central to our understanding of the development and function of many …

A practical method for position-dependent Compton-scatter correction in single photon emission CT

K Ogawa, Y Harata, T Ichihara, A Kubo… - IEEE transactions on …, 1991 - ieeexplore.ieee.org
A new method is proposed to subtract the count of scattered photons from that acquired with
a photopeak window at each pixel in each planar image of single-photon emission …

Tracking mesoderm induction and its specification to the hemangioblast during embryonic stem cell differentiation

HJ Fehling, G Lacaud, A Kubo, M Kennedy… - 2003 - journals.biologists.com
The hematopoietic and endothelial lineages derive from mesoderm and are thought to
develop through the maturation of a common progenitor, the hemangioblast. To investigate the …

Femtosecond imaging of surface plasmon dynamics in a nanostructured silver film

A Kubo, K Onda, H Petek, Z Sun, YS Jung, HK Kim - Nano letters, 2005 - ACS Publications
Light interacting with nanostructured metals excites the collective charge density fluctuations
known as surface plasmons (SP). Through excitation of the localized SP eigenmodes …

BMP-4 is required for hepatic specification of mouse embryonic stem cell–derived definitive endoderm

…, P Gadue, D Nierhoff, CI Koehler, A Kubo… - Nature …, 2006 - nature.com
When differentiated in the presence of activin A in serum-free conditions, mouse embryonic
stem cells efficiently generate an endoderm progenitor population defined by the …

Olivine‐wadsleyite transition in the system (Mg,Fe)2SiO4

…, O Nishikawa, M Song, A Kubo… - Journal of …, 2004 - Wiley Online Library
Phase relations of the olivine‐wadsleyite transition in the system (Mg,Fe) 2 SiO 4 have been
determined at 1600 and 1900 K using the quench method in a Kawai‐type high‐pressure …

The role of the sentinel lymph node in gastrointestinal cancer

…, K Kumai, T Ikeda, T Nakahara, A Kubo… - Surgical Clinics of North …, 2000 - Elsevier
The sentinel node concept has been validated in the fields of breast cancer and malignant
melanoma. % To date, application of the sentinel lymphadenectomy is considered to be one …

Femtosecond microscopy of surface plasmon polariton wave packet evolution at the silver/vacuum interface

A Kubo, N Pontius, H Petek - Nano letters, 2007 - ACS Publications
A movie of the dispersive and dissipative propagation of surface plasmon polariton (SPP)
wave packets at a silver/vacuum interface is recorded by the interferometric time-resolved …

Stable expression of HIF-1α in tubular epithelial cells promotes interstitial fibrosis

…, K Nakatani, K Harada, A Kubo… - American Journal …, 2008 - journals.physiology.org
Chronic hypoxia accelerates renal fibrosis. The chief mediator of the hypoxic response is
hypoxia-inducible factor 1 (HIF-1) and its oxygen-sensitive component HIF-1α. HIF-1 regulates …