Peptide receptor radionuclide therapy in vitro using [111In-DTPA0] octreotide

A Capello, EP Krenning, WAP Breeman… - Journal of Nuclear …, 2003 - Soc Nuclear Med
Peptide receptor radionuclide therapy (PRRT) using [ 111 In-DTPA 0 ]octreotide (where
DTPA is diethylenetriaminepentaacetic acid) is feasible because, besides γ-radiation, 111 In …

111In-labelled somatostatin analogues in a rat tumour model: somatostatin receptor status and effects of peptide receptor radionuclide therapy

A Capello, E Krenning, B Bernard, JC Reubi… - European journal of …, 2005 - Springer
111In-labelled somatostatin analogues in a rat tumour model: somatostatin receptor status
and effects of peptide receptor radionuclide therapy | European Journal of Nuclear Medicine …

Bile acid-stimulated expression of the farnesoid X receptor enhances the immune response in Barrett esophagus

A Capello, LMG Moons, A Van de Winkel… - Official journal of the …, 2008 - journals.lww.com
OBJECTIVES Barrett's esophagus (BE) is a premalignant condition of the esophagus. It is a
consequence of mucosal injury from chronic gastroesophageal reflux in which bile acids are …

Anticancer activity of targeted proapoptotic peptides

A Capello, EP Krenning, BF Bernard… - Journal of Nuclear …, 2006 - Soc Nuclear Med
Tumor-induced angiogenesis can be targeted by RGD (Arg-Gly-Asp) peptides, which bind
to α v β 3 -receptors upregulated on angiogenic endothelial cells. RGD-containing peptides …

[HTML][HTML] Expression, localization and polymorphisms of the nuclear receptor PXR in Barrett's esophagus and esophageal adenocarcinoma

A van de Winkel, V Menke, A Capello, LMG Moons… - BMC …, 2011 - Springer
Background The continuous exposure of esophageal epithelium to refluxate may induce
ectopic expression of bile-responsive genes and contribute to the development of Barrett's …

Radiolabeled RGD-DTPA-Tyr3-Octreotate for Receptor-Targeted Radionuclide Therapy

B Bernard, A Capello, M van Hagen… - Cancer Biotherapy …, 2004 - liebertpub.com
The aim of this study was to develop and investigate a radiopeptide for the treatment of cancers
which overexpress cell surface somatostatin receptors. The new radiopharmaceutical is …

Increased cell death after therapy with an Arg-Gly-Asp-linked somatostatin analog

A Capello, EP Krenning, BF Bernard… - Journal of Nuclear …, 2004 - Soc Nuclear Med
Receptor-targeted scintigraphy and radionuclide therapy with radiolabeled somatostatin
analogs are successfully applied for somatostatin receptor-positive tumors. The synergistic …

Anti‐tumor effect and increased survival after treatment with [177Lu‐DOTA0,Tyr3]octreotate in a rat liver micrometastases model

WAP Breeman, A Mearadji, A Capello… - … journal of cancer, 2003 - Wiley Online Library
Peptide receptor scintigraphy with [ 111 In‐DTPA 0 ]octreotide (a stabilized radiolabeled
somatostatin (SS) analogue, OctreoScan®) is widely used for the visualization and staging of …

Tyr3-Octreotide and Tyr3-Octreotate Radiolabeled with 177Lu or 90Y: Peptide Receptor Radionuclide Therapy Results In Vitro

A Capello, EP Krenning, WAP Breeman… - Cancer Biotherapy …, 2003 - liebertpub.com
Somatostatin analogs promising for peptide receptor scintigraphy (PRS) and peptide receptor
radionuclide therapy (PRRT) are D-Phe-c(Cys-Tyr-D-Trp-Lys-Thr-Cys)-Thr(ol) (Tyr 3 -…

A genome-wide screening in Saccharomyces cerevisiae for genes that confer resistance to the anticancer agent cisplatin

H Burger, A Capello, PW Schenk, G Stoter… - Biochemical and …, 2000 - Elsevier
Cisplatin is a potent DNA-damaging agent that has demonstrated anticancer activities
against several tumors. However, manifestation of cellular resistance is a major obstacle in …