Screening for distant metastases in head and neck cancer patients by chest CT or whole body FDG-PET: a prospective multicenter trial

A Senft, R de Bree, OS Hoekstra, DJ Kuik… - Radiotherapy and …, 2008 - Elsevier
BACKGROUND AND PURPOSE: The aim of the study was to define the added value of
whole body FDG-PET in screening for distant metastases in patients with head and neck …

Screening for distant metastases in patients with head and neck cancer: Is there a role for 18FDG-PET?

J Brouwer, A Senft, R De Bree, EFI Comans… - Oral oncology, 2006 - Elsevier
The detection of distant metastases and second primary tumours at the time of initial evaluation
changes the prognosis and influences the selection of treatment modality in patients with …

Pretreatment screening on distant metastases and head and neck cancer patients: validation of risk factors and influence on survival

TT Peters, A Senft, OS Hoekstra, JA Castelijns, BI Witte… - Oral Oncology, 2015 - Elsevier
Background and purpose Previously identified high risk factors for development of distant
metastases are: three or more lymph node metastases, bilateral lymph node metastases, …

Chest CT and whole-body 18F-FDG PET are cost-effective in screening for distant metastases in head and neck cancer patients

CA Uyl-de Groot, A Senft, R de Bree… - Journal of Nuclear …, 2010 - Soc Nuclear Med
The aim of the study was to define the cost-effectiveness of whole-body 18 F-FDG PET, as
compared with chest CT, in screening for distant metastases in patients with head and neck …

Expression profiling and prediction of distant metastases in head and neck squamous cell carcinoma

BJM Braakhuis, A Senft, R de Bree, J de Vries… - Journal of clinical …, 2006 - jcp.bmj.com
Background: For breast and prostate cancer, a gene expression signature of the tumour is
associated with the development of distant metastases. Regarding head and neck squamous …

Detection of distant metastases in head and neck cancer: changing landscape

R de Bree, A Senft, A Coca-Pelaz, L Kowalski… - Advances in …, 2018 - Springer
As head and neck squamous cell carcinoma (HNSCC) patients with distant metastases (DM)
were generally treated only palliatively, the value of screening for DM was usually limited to …

[HTML][HTML] Screening for distant metastases in head and neck cancer patients using FDG-PET and chest CT: validation of an algorithm

A Senft, OS Hoekstra, BI Witte, CR Leemans… - European Archives of …, 2016 - Springer
In patients with head and neck squamous cell carcinoma and high-risk factors, the combination
of whole body FDG-PET and contrast-enhanced chest CT has the highest sensitivity and …

[HTML][HTML] Interobserver variability in chest CT and whole body FDG-PET screening for distant metastases in head and neck cancer patients

A Senft, R De Bree, RP Golding, EFI Comans… - Molecular Imaging and …, 2011 - Springer
Purpose The aim of the study was to assess the interobserver variability in chest computed
tomography (CT) and whole body 2-deoxy-2-[ 18 F]fluoro-d-glucose positron emission …

[HTML][HTML] The adverse impact of surveillance intervals on the sensitivity of FDG-PET/CT for the detection of distant metastases in head and neck cancer patients

A Senft, G Yildirim, OS Hoekstra, JA Castelijns… - European Archives of …, 2017 - Springer
The presence of distant metastases at initial evaluation influences treatment selection, since
no effective systemic treatment for disseminated head and neck squamous cell carcinoma (…

[HTML][HTML] Pretreatment screening for distant metastases in the Dutch head and neck centers: 10 years later

A Senft, OS Hoekstra, JA Castelijns… - European Archives of …, 2016 - Springer
To evaluate the current practice and change in practice concerning screening for distant
metastases in head and neck squamous cell carcinoma patients, we performed a survey with …