Multimodality imaging and, more specifically, the combination of PET and CT has matured
into an important diagnostic tool. During the same period, concepts for PET scanners …

BACKGROUND AND AIMS: Pancreatic ductal adenocarcinoma (PDAC) is a highly desmoplastic
tumor with an innate resistance to therapy. Pancreatic stellate cells (PSCs) produce this …

Chronic inflammation is accompanied by impaired T-cell immunity. In the mouse, myeloid
cell-associated arginase accounts for the suppression of immune reactivity in various models …

Simultaneous PET and MRI using new hybrid PET/MRI systems promises optimal spatial and
temporal coregistration of structural, functional, and molecular image data. In a pilot study …

Background and aims: Emerging evidence suggests that highly treatment-resistant tumour-initiating
cells (TICs) play a central role in the pathogenesis of pancreatic cancer. Tumour …

Multimodal imaging is now well-established in routine clinical practice. Especially in the
field of nuclear medicine, new positron emission tomography (PET) installations comprise …

BACKGROUND/AIMS: The integrin αvβ6 promotes proliferation of specialized epithelia and
acts as a receptor for the activation of latent TGFβ1. We studied αvβ6 expression in …

Objectives Technical performance evaluation of a human brain PET/MRI system. Methods
The magnetic field compatible positron emission tomography (PET) insert is based on …

Tissue fibrosis is one of the characteristics of chronic pancreatitis and pancreatic adenocarcinoma.
Activated pancreatic stellate cells (PSC) play a central role in this process. However, …

Given the need for sophisticated in vivo detection techniques to better characterize the cellular
and subcellular processes in animals and humans, molecular imaging has become an …