We have developed a novel microfluidic device constructed from poly(dimethylsiloxane)
using multilayer soft lithography technology for the analysis of single cells. The microfluidic …

An integrated elastomeric microfluidic device, with a footprint the size of a postage stamp,
has been designed and optimized for multistep radiosynthesis of PET tracers. Methods: The …

Microreactor technology has shown potential for optimizing synthetic efficiency, particularly
in preparing sensitive compounds. We achieved the synthesis of an [ 18 F]fluoride-…

A new, versatile architecture is presented for microfluidic devices made entirely from glass,
for use with reagents which would prove highly corrosive for silicon. Chips consist of three …

The Berthelot reaction is a well-established colorimetric method for the determination of
ammonia. It has been investigated with the particular aim of incorporating it into a simple, …

ABL is the main target of several tyrosine kinase inhibitors used in the treatment of chronic
myeloid leukemia (CML) patients. ABL tyrosine kinase domain (TKD) point mutations are the …

Progress in the development of a micro-fluidic system for colorimetric monitoring of ammonia
in drinking and wastewater is described. The ultimate goal is to have a miniaturised …

We present numerical modeling and experimental studies of flow optimization inside a batch
microfluidic micro-reactor used for synthesis of human-scale doses of Positron Emission …

… Quake, Stanford, CA (US); Hsian-rong Tseng, I os Angeles, CA (US); Paul Wyatt,
Tipperary (IE); Antoine Daridon, Mont-Sur-Rolle (CH) (73) Assignees: Fluidigm Corporation …

Point mutations in the Abl tyrosine kinase domain are the main mechanism of secondary
resistance to imatinib mesylate (IM) therapy in chronic myeloid leukemia (CML) patients. …