Theranostic applications of nanomaterials in cancer: drug delivery, image-guided therapy, and multifunctional platforms

…, R Manchanda, AJ McGoron - Applied biochemistry …, 2011 - Springer
Successful cancer management depends on accurate diagnostics along with specific
treatment protocols. Current diagnostic techniques need to be improved to provide earlier …

Preparation and characterization of a polymeric (PLGA) nanoparticulate drug delivery system with simultaneous incorporation of chemotherapeutic and thermo-optical …

…, A Nagesetti, AJ McGoron - Colloids and Surfaces B …, 2010 - Elsevier
The objective of this study was to develop biodegradable poly(dl-lactide-co-glycolic acid) (PLGA)
nanoparticles simultaneously loaded with indocyanine green (ICG) and doxorubicin (…

[HTML][HTML] Combined effects of laser-ICG photothermotherapy and doxorubicin chemotherapy on ovarian cancer cells

Y Tang, AJ McGoron - Journal of Photochemistry and Photobiology B …, 2009 - Elsevier
Doxorubicin (DOX) is an anthracycline antibiotic widely used in cancer chemotherapy. Its use
is limited by cardiac toxicity and drug resistance. Hyperthermia can aid the functionality of …

Arsenic speciation on silver nanofilms by surface-enhanced Raman spectroscopy

…, V Liamtsau, C Fan, KL Sylvers, AJ McGoron… - Analytical …, 2019 - ACS Publications
Surface-enhanced Raman spectroscopy (SERS), as a nondestructive and fast detection
technique, is a promising alternative approach for arsenic detection, particularly for in situ …

Comparative study of the optical and heat generation properties of IR820 and indocyanine green

…, Y Tang, SZR Kazmi, AJ McGoron - Molecular …, 2012 - journals.sagepub.com
Near-infrared (NIR) fluorophores are the focus of extensive research for combined molecular
imaging and hyperthermia. In this study, we showed that the cyanine dye IR820 has optical …

Comparing cellular uptake and cytotoxicity of targeted drug carriers in cancer cell lines with different drug resistance mechanisms

…, A Fernandez-Fernandez, AJ McGoron - … , Biology and Medicine, 2011 - Elsevier
The purpose of this study was to compare the cellular uptake and cytotoxicity of targeted and
nontargeted doxorubicin (DOX)-loaded poly(d,l-lactide co-glycolide) (PLGA) nanoparticle (…

Simultaneous Delivery of Chemotherapeutic and Thermal-Optical Agents to Cancer Cells by a Polymeric (PLGA) Nanocarrier: An In Vitro Study

…, S Srinivasan, AJ McGoron - Pharmaceutical …, 2010 - Springer
Purpose To test the effectiveness of a dual–agent-loaded PLGA nanoparticulate drug
delivery system containing doxorubicin (DOX) and indocyanine green (ICG) in a DOX-sensitive …

[HTML][HTML] Magneto-plasmonic nanostars for image-guided and NIR-triggered drug delivery

…, H Arami, A Ahmadivand, N Pala, AJ McGoron… - Scientific Reports, 2020 - nature.com
Smart multifunctional nanoparticles with magnetic and plasmonic properties assembled on
a single nanoplatform are promising for various biomedical applications. Owing to their …

In-vivo assessment of a novel polymer (SIBS) trileaflet heart valve.

Q Wang, AJ McGoron, R Bianco, Y Kato… - The Journal of heart …, 2010 - europepmc.org
Methods Four SIBS valves (two with surface modification using dimyristoyl phosphatidylcholine,
DMPC), and two commercial Magna tissue valves, were implanted into sheep. …

Multifunctional surface-enhanced raman spectroscopy-detectable silver nanoparticles for combined photodynamic therapy and pH-triggered chemotherapy

…, A Fernandez-Fernandez, AJ McGoron - Journal of …, 2016 - ingentaconnect.com
This research paper reports the development of a multifunctional anti-cancer prodrug
system based on silver nanoparticles. This prodrug system is composed of 70-nm sized …