The NCCN Clinical Practice Guidelines in Oncology (NCCN Guidelines) for Neuroendocrine
and Adrenal Gland Tumors focus on the diagnosis, treatment, and management of patients …

We recently cloned a novel pituitary tumor transforming gene (PTTG). Here we report PTTG
expression in human pituitary adenomas and in normal pituitary tissue. In situ hybridization …

Pituitary tumors are commonly encountered, and result from clonal expansion of a single
mutated cell 1. Hypothalamic hormones, local growth factors and circulating sex steroid …

Background Pituitary tumours are common and easily treated by surgery or medical treatment
in most cases. However, a small subset of pituitary tumours does not respond to standard …

The 13th Acromegaly Consensus Conference was held in November 2019 in Fort
Lauderdale, Florida, and comprised acromegaly experts including endocrinologists and …

Objective The aim of the Acromegaly Consensus Group was to revise and update the
consensus on diagnosis and treatment of acromegaly comorbidities last published in 2013. …

There have been significant developments in diagnostic and therapeutic options for patients
with neuroendocrine tumors (NETs). Key phase 3 studies include the CLARINET trial, which …

Somatostatin receptor (SSTR) PET has demonstrated a significant improvement over
conventional imaging (CI) in patients with neuroendocrine tumors (NETs). SSTR PET should …

Management of neuroendocrine neoplasia represents a clinical challenge because of its
late presentation, lack of treatment options, and limitations in present imaging modalities and …

Pituitary hyperplasia and lactotroph replication are induced by estrogen. The product of the
pituitary tumor transforming gene (PTTG) exhibits in vitro and in vivo transforming activity and …