Idiopathic REM sleep behaviour disorder (iRBD) is a powerful early sign of Parkinson’s
disease, dementia with Lewy bodies, and multiple system atrophy. This provides an …

Background Increasing evidence connects the gut microbiota and the onset and/or phenotype
of Parkinson's disease (PD). Differences in the abundances of specific bacterial taxa have …

Patients with isolated rapid-eye-movement sleep behaviour disorder (RBD) are commonly
regarded as being in the early stages of a progressive neurodegenerative disease involving α…

Phosphorylated alpha-synuclein (p-alpha-syn) deposits, one of the neuropathological hallmarks
of Parkinson’s disease (PD), have recently been detected in dermal nerve fibres in PD …

The neurodegenerative synucleinopathies, including Parkinson’s disease and dementia
with Lewy bodies, are characterized by a typically lengthy prodromal period of progressive …

Objective This multilanguage study used simple speech recording and high‐end pattern
analysis to provide sensitive and reliable noninvasive biomarkers of prodromal versus manifest …

Rapid-eye movement (REM) sleep behavior disorder (RBD), enactment of dreams during
REM sleep, is an early clinical symptom of alpha-synucleinopathies and defines a more …

Idiopathic REM sleep behavior disorder (iRBD) is considered a prodromal stage of
Parkinson disease (PD) and other Lewy body disorders. Spatial covariance analysis of 18 F-FDG …

Objective This study was undertaken to follow up predictive factors for α‐synuclein–related
neurodegenerative diseases in a multicenter cohort of idiopathic/isolated rapid eye …

IMPORTANCE Nonmotor symptoms of Parkinson disease (PD) often predate the movement
disorder by decades. Currently, there is no blood biomarker to define this prodromal phase. …