An automated tool for detection of FLAIR-hyperintense white-matter lesions in multiple sclerosis
In Multiple Sclerosis (MS), detection of T2-hyperintense white matter (WM) lesions on
magnetic resonance imaging (MRI) has become a crucial criterion for diagnosis and predicting …
magnetic resonance imaging (MRI) has become a crucial criterion for diagnosis and predicting …
Perfusion abnormalities in mild cognitive impairment and mild dementia in Alzheimer's disease measured by pulsed arterial spin labeling MRI
P Alexopoulos, C Sorg, A Förschler, T Grimmer… - European archives of …, 2012 - Springer
Alzheimer’s disease (AD) and mild cognitive impairment (MCI), the transitional clinical stage
between cognition in normal aging and dementia, have been linked to abnormalities in …
between cognition in normal aging and dementia, have been linked to abnormalities in …
Intradural spinal tumors in adults—update on management and outcome
…, FH Ruppert, S Schreiber, A Förschler… - Neurosurgical …, 2019 - Springer
Among spinal tumors that occur intradurally, meningiomas, nerve sheath tumors, ependymomas,
and astrocytomas are the most common. While a spinal MRI is the state of the art to …
and astrocytomas are the most common. While a spinal MRI is the state of the art to …
Progression of cerebral amyloid load is associated with the apolipoprotein E ε4 genotype in Alzheimer's disease
…, S Tholen, BH Yousefi, P Alexopoulos, A Förschler… - Biological …, 2010 - Elsevier
BACKGROUND: Pittsburgh Compound B ([ 11 C] PiB) is a specific positron emission tomography
(PET) marker of cerebral amyloid deposits. Only few data have been published on in …
(PET) marker of cerebral amyloid deposits. Only few data have been published on in …
Permanent middle cerebral artery occlusion in sheep: a novel large animal model of focal cerebral ischemia
J Boltze, A Förschler, B Nitzsche… - Journal of Cerebral …, 2008 - journals.sagepub.com
As effective stroke treatment by thrombolysis is bound to a narrow time window excluding
most patients, numerous experimental treatment strategies have been developed to gain new …
most patients, numerous experimental treatment strategies have been developed to gain new …
Postoperative ischemic changes following resection of newly diagnosed and recurrent gliomas and their clinical relevance
J Gempt, A Förschler, N Buchmann, H Pape… - Journal of …, 2013 - thejns.org
Object The aim of surgical treatment of glioma is the complete resection of tumor tissue with
preservation of neurological function. Inclusion of diffusion-weighted imaging (DWI) in the …
preservation of neurological function. Inclusion of diffusion-weighted imaging (DWI) in the …
MR-based hypoxia measures in human glioma
V Tóth, A Förschler, NM Hirsch, J Den Hollander… - Journal of neuro …, 2013 - Springer
Hypoxia plays a central role in tumor stem cell genesis and is related to a more malignant
tumor phenotype, therapy resistance (eg in anti-angiogenic therapies) and radio-insensitivity. …
tumor phenotype, therapy resistance (eg in anti-angiogenic therapies) and radio-insensitivity. …
Technical considerations on the validity of blood oxygenation level‐dependent‐based MR assessment of vascular deoxygenation
NM Hirsch, V Toth, A Förschler, H Kooijman… - NMR in …, 2014 - Wiley Online Library
A blood oxygenation level‐dependent (BOLD)‐based apparent relative oxygen extraction
fraction (rOEF) as a semi‐quantitative marker of vascular deoxygenation has recently been …
fraction (rOEF) as a semi‐quantitative marker of vascular deoxygenation has recently been …
Long-term benefit of human fetal neuronal progenitor cell transplantation in a clinically adapted model after traumatic brain injury
…, F Scheidt, H Hilbig, J Boltze, A Förschler… - Journal of …, 2011 - liebertpub.com
Experimental human fetal neural progenitor cell (hfNPC) transplantation has proven to be a
promising therapeutic approach after traumatic brain injury (TBI). However, the long-term …
promising therapeutic approach after traumatic brain injury (TBI). However, the long-term …
Determination of the therapeutic time window for human umbilical cord blood mononuclear cell transplantation following experimental stroke in rats
…, D Lobsien, DC Wagner, A Förschler… - Cell …, 2012 - journals.sagepub.com
Experimental treatment strategies using human umbilical cord blood mononuclear cells (hUCB
MNCs) represent a promising option for alternative stroke therapies. An important point …
MNCs) represent a promising option for alternative stroke therapies. An important point …