Tumor-associated macrophages constitute a major component of the stroma of solid tumors,
encompassing distinct subpopulations with different characteristics and functions. We …

Introduction Radiolabeled nanobodies are exciting new probes for molecular imaging due to
high affinity, high specificity and fast washout from the blood. Here we present the labeling …

Aims Positron emission tomography–computed tomography (PET-CT) is a highly sensitive
clinical molecular imaging modality to study atherosclerotic plaque biology. Therefore, we …

Purpose Macrophage mannose receptor (MMR, CD206) expressing tumor-associated
macrophages (TAM) are protumorigenic and was reported to negatively impact therapy …

Radiolabeling of nanobodies with radiometals by chelation has the advantage of being
simple, fast and easy to implement in clinical routine. In this study, we validated 68 Ga/ 111 In-…

… These authors contributed equally Correspondence should be directed to Anneleen
Blykers: In … Tel: +32 2 477 4991; fax: +32 2 477 5017 E-mail address: anneleen.blykers@gmail.com …

1476 Objectives The most widely used radiopharmaceutical in oncology, 18F-FDG, is
relatively suboptimal for detecting tumors in the brain due to the glycolytic metabolism in the …

Abstract Body: Introduction: Single domain camelid antibody fragments, nanobodies (nb) have
proven to be powerful probes tools for molecular imaging and are being tested in targeted …

Purpose: Cardiac tests for diagnosing myocarditis lack sensitivity or specificity. We hypothesized
that contrast enhanced ultrasound molecular imaging (CEUMI) could detect endothelial …

Objectives Demonstrating tumor hypoxia in vivo in a non-invasive manner by 18F-FMISO-PET
can be used to predict resistance to radiotherapy. The automated synthesis of 18F-FMISO …