Glial cells in the gut

A Rühl - Neurogastroenterology & Motility, 2005 - Wiley Online Library
The enteric nervous system is composed of both neurons and glia. Recent evidence indicates
that enteric glia–which vastly outnumber enteric neurons–are actively involved in the …

Role of enteric glia in intestinal physiology: effects of the gliotoxin fluorocitrate on motor and secretory function

…, WK MacNaughton, A Ruhl… - American Journal …, 2006 - journals.physiology.org
The role of enteric glia in gastrointestinal physiology remains largely unexplored. We
examined the actions of the gliotoxin fluorocitrate (FC) on intestinal motility, secretion, and …

Quantitative assessment of glial cells in the human and guinea pig enteric nervous system with an anti‐Sox8/9/10 antibody

…, M Schemann, K Michel, A Rühl - Journal of …, 2008 - Wiley Online Library
Quantitative changes of enteric glia (EGC) have been implicated in gastrointestinal
disorders. To facilitate future studies of EGC in human pathology, we aimed to characterize …

Enteric glia regulate intestinal barrier function and inflammation via release of S-nitrosoglutathione

TC Savidge, P Newman, C Pothoulakis, A Ruhl… - Gastroenterology, 2007 - Elsevier
Background & Aims: Barrier functions across epithelia and endothelia are essential for
homeostatic tissue regulation. Astroglia interact with cerebral endothelia to maintain the blood-…

Unipedal stance testing as an indicator of fall risk among older outpatients

EA Hurvitz, JK Richardson, RA Werner, AM Ruhl… - Archives of physical …, 2000 - Elsevier
Objective: To test the hypothesis that a decreased unipedal stance time (UST) is associated
with a history of falling among older persons. Design: Fifty-three subjects underwent a …

Interleukin-13 and transforming growth factor β synergise in the pathogenesis of human intestinal fistulae

…, J Arikkat, P Frei, M Fried, A Weber, E Jehle, A Rühl… - Gut, 2013 - gut.bmj.com
Objective Epithelial to mesenchymal transition (EMT) seems to play an important role in the
pathogenesis of fistulae, a common clinical complication of Crohn's disease (CD). TGFβ and …

Enteric glia inhibit intestinal epithelial cell proliferation partly through a TGF-β1-dependent pathway

…, T Wedel, P Naveilhan, A Ruhl… - American Journal …, 2007 - journals.physiology.org
Although recent studies have shown that enteric neurons control intestinal barrier function,
the role of enteric glial cells (EGCs) in this control remains unknown. Therefore, our goal was …

Prognostic aspects of 18F-FDG PET kinetics in patients with metastatic colorectal carcinoma receiving FOLFOX chemotherapy

…, LG Strauss, C Burger, A Rühl… - Journal of Nuclear …, 2004 - Soc Nuclear Med
We evaluated quantitative measurement series (MS) with 18 F-FDG and PET and compared
different quantification methods for prediction of individual survival in patients with …

Functional expression of the peptide transporter PEPT2 in the mammalian enteric nervous system

A Rühl, S Hoppe, I Frey, H Daniel… - Journal of …, 2005 - Wiley Online Library
The peptide transporter PEPT2 mediates transmembrane uptake of small peptides. So far,
its expression has not been evidenced in the gastrointestinal tract. We have investigated …

Experimental study of heat transport in catalytic sponge packings by monitoring spatial temperature profiles in a cooled-wall reactor

I Gräf, AK Rühl, B Kraushaar-Czarnetzki - Chemical Engineering Journal, 2014 - Elsevier
The heat transport characteristics of catalytically coated sponge packings and of a packed
bed of spherical shell-catalysts were investigated by performing the exothermal …