The treatment of central nervous system (CNS) disease has long been difficult due to the
ineffectiveness of drug delivery across the blood-brain barrier (BBB). This review summarizes …

Idiopathic pulmonary fibrosis (IPF) is a progressive fibrotic lung disease where invasive
pulmonary myofibroblasts secrete collagen and destroy lung integrity. Here, we show that …

Targeting nanoparticles (NPs) loaded with drugs and probes to precise locations in the body
may improve the treatment and detection of many diseases. Generally, to achieve targeting, …

Introduction: Brain tumors are inherently difficult to treat in large part due to the cellular blood–brain
barriers (BBBs) that limit the delivery of therapeutics to the tumor tissue from the …

Targeting of therapeutics or imaging agents to the endothelium has the potential to improve
specificity and effectiveness of treatment for many diseases. One strategy to achieve this …

More than one-third of the world’s population is exposed to Plasmodium vivax malaria, mainly
in Asia 1 . P. vivax preferentially invades reticulocytes (immature red blood cells) 2 , 3 – 4 . …

Vascular inflammation is a common, complex mechanism involved in pathogenesis of a
plethora of disease conditions including ischemia–reperfusion, atherosclerosis, restenosis and …

Purpose Chemotherapeutic adjuvants, such as oxaliplatin (OXA) and 5-fluorouracil (5-FU),
that enhance the immune system, are being assessed as strategies to improve durable …

The use of targeted therapeutics to replenish pathologically deficient proteins on the luminal
endothelial membrane has the potential to revolutionize emergency and cardiovascular …

Isotopically labeled nanomaterials have recently attracted much attention in biomedical
research, environmental health studies, and clinical medicine because radioactive probes allow …