Neutrophils play a key role in defence against infection and in the activation and regulation
of innate and adaptive immunity. In cancer, tumour-associated neutrophils (TANs) have …

CD69 was initially described as being restricted to recently activated lymphoid cells, but is
now known to be expressed on the surface of all hematopoietically derived leukocytes. …

Intracellular pathways leading from membrane receptor engagement to apoptotic cell death
are still poorly characterized. We investigated the intracellular signaling generated after …

In this paper we report on the cloning and characterization of mouse CCR8. Like its human
homologue, it is predominantly expressed in the thymus. In the periphery, murine CCR8 …

There is much evidence to support a role for natural killer (NK) cells in controlling the
progression of multiple myeloma (MM), a malignancy characterized by an abnormal plasma cell …

The chemokine CXC ligand 8 (CXCL8)/IL-8 and related agonists recruit and activate
polymorphonuclear cells by binding the CXC chemokine receptor 1 (CXCR1) and CXCR2. Here we …

1α,25‐Dihydroxyvitamin D 3 [1 2 25‐(OH) 2 D 3 ] exerts several effects on the immune
system, by regulating lymphocyte proliferation, differentiation of monocytes and secretion of …

The effects of human recombinant tumor necrosis factor (TNF-α) on the synaptic transmission
were studied in rat hippocampal slices by using extracellular field potential recordings. …

Recent evidence indicates that natural killer (NK) cells can negatively regulate T-cell
responses, but the mechanisms behind this phenomenon as a consequence of NK–T-cell …

It is important to understand which molecules are relevant for linking innate and adaptive
immune cells. In this study, we show that OX40 ligand is selectively induced on IL-2, IL-12, or IL-…