BACKGROUND: The purpose of this study was to analyze the effects of changes in the
diagnosis and treatment of pheochromocytoma in a pediatric population. METHODS: We …

The MYC family oncogenes cause transformation and tumor progression by corrupting
multiple cellular pathways, altering cell cycle progression, apoptosis, and genomic instability. …

Hepatocellular carcinoma (HCC) is a significant cause of morbidity and mortality worldwide,
with limited therapeutic options for advanced disease. Targeted α-therapy is an emerging …

Glypican-3 (GPC3) is a tumor associated antigen expressed by hepatocellular carcinoma (HCC)
cells. This preclinical study evaluated the efficacy of a theranostic platform using a …

Secreted proteins such as growth factors, cytokines, and chemokines play important roles in
tumor development. Through expression microarray and bioinformatic analysis, we …

Hepatocellular carcinoma (HCC) is the second most lethal malignancy globally and is
increasing in incidence in the United States. Unfortunately, there are few effective systemic …

Background Early intrahepatic recurrence is common after surgical resection of hepatocellular
carcinoma (HCC) and leads to increased morbidity and mortality. Insensitive and …

Recently, two large, multicenter prospective ran-domized controlled trials were published in
the Journal of the American Medical Association regarding the comparison of the use of …

Staphylococcus aureus is a commensal skin bacterium that most commonly colonizes the
anterior nares. Patients colonized with S. aureus carry an increased risk of nosocomial and …

The purpose of this study is to develop a thorium-227 ( 227 Th) antibody radioimmunoconjugate
targeting glypican-3 (GPC3) and to test its therapeutic efficacy in a hepatocellular …