The widely used Logan plot in radioligand receptor dynamic PET studies produces marked
noise-induced negative biases in the estimates of total distribution volume (DV T ) and …

BACKGROUND:: Equilibrium analysis to quantify dynamic positron emission tomography (PET)
with bolus followed by continuous tracer infusion and acute amphetamine challenge …

Utilizing postmortem data (Breese et al. [2000] Neuropsychopharmacology 23:351–364),
we hypothesized that the densities of high‐affinity neuronal α4β2 nicotinic acetylcholine …

(S)‐5‐[ 123 I]iodo‐3‐(2‐azetidinylmethoxy)pyridine (5‐[ 123 I]IA), a novel potent radioligand
for high‐affinity α4β2* neuronal nicotinic acetylcholine receptors (nAChRs), provides a …

We present a new multiresolution visualization design which allows a user to control the
physical data resolution as well as the logical display resolution of multivariate data. A system …

[/sup 123/I]5-IA-85380 ([/sup 123/I]5-IA) is a ligand specific for the /spl alpha/4/spl beta/2
nicotinic acetylcholine receptor (nAChR) subtype. It was reported that distribution volume (DV) is …

(S)-5-[123 I] iodo-3-(2-azetidinylmethoxy) pyridine (5-[123 I] IA), a novel potent radioligand for
high-affinity α4β2* neuronal nicotinic acetylcholine receptors (nAChRs), provides a means …

Aims RPR 102681, a cholecystokinin‐B antagonist, increased dopamine (DA) release and
reduced cocaine self‐administration in animals. This pilot study sought to assess the safety …

We describe a computer system designed to meet the data processing needs of a high-volume
brain PET research center based on the High Resolution Research Tomograph (HRRT). …

The side effects of sedation induced by antihistamine drugs are considered due to their
occupation on cerebral H1 receptor. To evaluate the pharmacological effects of antihistamines …